The recent advances in nanotechnology and the corresponding popular usage of nanomaterials have resulted in uncertainties regarding their environmental impacts. In this study, we used a systematic approach to study and compare the in vitro cytotoxicity of selected engineered metal oxide nanoparticles to the test organisms--E. coli. Among the seven test nano-sized metal oxides, ZnO, CuO, Al2O3, ...

The selective effects of 24 agents on mouse spleen effector functions involved in the immune responses to sheep erythrocytes have been demonstrated. Five tests were used to assay the effector functions: the comple ment-dependent cellular cytotoxicity test, which mea sures complement-mediated lysis in the presence of anti body excreted from B-cell effectors; the complement-in dependent cellular ...

Corrosion phenomenon is the important factor in the field of biomaterial applications. The corrosion resistance of the metallic glasses was investigated by the cyclic voltammetry and a low-voltage potential state test of the cell membrane potential simulation in the simulation body fluid Hank’s solution in this paper. The potential Tiand Zr-based metallic glasses were screened rapidly to test t...

Background: Berberine and Nano-curcumin are two herbal medicines with strong anti-cancer effects on tumor cells, but low toxicity on normal cells, when used alone. Breast cancer is known as the most common cancer in women and second deadly one. In this study, we evaluated the cytotoxicity effects of combination Berberine and Nano-curcumin in breast cancer cell line to see whether they have furt...

Cytotoxicity presents one of the required criteria in biological evaluation medical devices. In this study, semi-direct contact test was used to evaluate potential cytotoxicity hydrogel wound dressings compared conventional extract test. Three types sheets were fabricated from poly(vinyl alcohol) (PVA) by gamma irradiation: Bare sheets, silver (Ag)-coated and Aloe vera (AV)-coated sheets. test,...

introduction: endodontic sealers are in direct contact with periradicular tissues and play a critical role in regeneration and pathogenesis of periradicular diseases. the aim of this study was to compare cytotoxicity of four different types of sealers including ah plus, sankin, tubliseal ewt and apexit as well as their effect on cytokine release of l929 fibroblasts. materials and methods: in th...

Workshop participants agreed that tests of basal cytotoxicity were sufficiently predictive for the rodent LD50 such that cytotoxicity tests could be used to predict a starting dose for an in vivo lethality assay (NIEHS, 2001). This section discusses how to proceed. Theoretically, any in vitro test capable of determining basal cytotoxicity could be used to determine the best estimate of a starti...

UNLABELLED The goal of this in vitro study was to evaluate the relative biocompatibility of four endodontic sealers on the cell culture of the human fibroblast through cytotoxicity. MATERIALS AND METHODS In this study four endodontics sealers was used GuttaFlow (Roeko)silicone based sealer, AH plus (De Tray-DENTSPLY) epoxy resin based, Apexit (Vivadent) calcium hydroxide based and Endorez (Ul...