N(G)-nitro-arginine (NNA) is known to exhibit stereoselective pharmacokinetics in which N(G)-nitro-d-arginine (d-NNA) has a faster clearance rate than N(G)-nitro-l-arginine (l-NNA) in anesthetized rats, and d-NNA undergoes unidirectional chiral inversion. It was postulated that chiral inversion of d-NNA was performed in a two-step pathway by d-amino acid oxidase (DAAO) followed by an unidentifi...

The 1H and natural-abundance 13C-NMR spectra of 1-thiacyclooctan-3-one (1) have been measured from 25 to -100°C. Coalescence is observed in the 1H-NMR spectra of (1) at about -80°C, and attributed to ring inversion in a boat-chair conformation, which is the predominant conformation of (1). The free energy of activation (DG¹</s...

There is growing interest in developing a three-dimensional (3-D) inversion and imaging technique from a single borehole. This problem can be solved by using tensor (multi-component) induction welllogging – TIWL. This method was originally introduced to resolve formation anisotropy. However, it was demonstrated in several publications that the TIWL instrument has sensitivity to 3-D conductivity...

One of the most challenging problems in electromagnetic (EM) geophysical methods is developing fast and stable methods of EM modeling and inversion for 3-D inhomo­ geneous geoelectrical structures. In this paper I present an overview of the research conducted by the Consortium for Electromagnetic Modeling and Inversion (CEMI) at the University of Utah on developing fast forward mod­ eling and i...

one of the bio-sensing mechanisms is mechanical. rather than measuring shift in resonance frequency, we adopt to measure the change in spring constant due to adsorption, as one of the fundamental sensing mechanism. this study explains  determination of spring constant of a surface functionalized micro machined micro cantilever, which resonates in a trapezoidal cavity-on silicon wafer, with the ...

We present the development of an algorithm for inverting multi-component gravity gradiometer data to recover three-dimensional (3-D) distributions of density contrast for salt imaging. The algorithm is a direct adaptation of the author’s earlier work on 3-D inversion of magnetic data. The underlying method is based upon a regularized inversion that constructs a density contrast distribution hav...

We present a method for the solution of 3-D controlled source magnetotelluric (CSAMT) inverse problems. The inverse problem is formulated as the minimization of a Tikhonov parametric functional with a focusing stabilizer. Observed CSAMT apparent resis­ tivities are converted to log-anomalous apparent resistivities, which are linearly connected to anomalous currents via the integral equation. We...

background one of the most important causes of mortality in developed and developing countries is coronary artery disease. coronary artery disease (cad) may develop by deposition of lipid, fibrous or calcified debris on the surface of the coronary artery lumen. fibrous plaque and calcified plaque may cause substantial stenosis of coronary arteries leading to ischemia of heart muscle while lipid...