forecasting of macroeconomic variables has specific importance in economic topics. indeed, different models are invented to forecast variables to help economic policy makers in adopting appropriate monetary and fiscal policies. in this paper, the performance of integrated model of input-output (io) and neural network is investigated in forecasting final demand and total production and the resul...

The contribution of specific HLA Class II alleles in type 1 diabetes is determined by polymorphic amino acid epitopes that direct antigen binding therefore, along with conventional allele frequency analysis, epitope analysis can provide important insights into disease susceptibility. We analyzed the highly heterogeneous Cypriot population for the HLA class II loci of T1DM patients and controls ...

The Leontief model is generally considered as belonging to the category of the production-prices models , aside of the Ricardian, Marxian and Sra aian models. This paper clearly demonstrates that this is a super cial point of view. As the Leontief model handles price indexes, it is over two periods: the Leontief price indexes solve the model for the base time period. The production-prices model...

This study evaluated the long-term cutaneous tolerance of a 0.0584% hydrocortisone aceponate spray (Cortavance®; Virbac) in dogs. Four healthy Beagle bitches were sprayed once daily for 56 days at label dose (260μl/100 cm2) on one-third of the body surface, at a distance of 10 cm from clipped skin areas. The animals were examined daily for general clinical signs and reaction at application site...

The Leontief model is generally considered as belonging to the category of the production-prices models , aside of the Ricardian, Marxian and Sra aian models. This paper clearly demonstrates that this is a super cial point of view. As the Leontief model handles price indexes, it is biperiodic: the Leontief price indexes solve the model for the base time period. The production-prices model that ...

Although there have been many elaborations of the basic input-output approach, including multi-regional models, dynamic models, models with variable coefficients, supply-side models, etc., these approaches all have the same limitation. The fixed-coefficients production function assumptions ignore substitutions in response to price changes that can be expected to accompany most shocks– skipping ...

To uncover the structural and dynamical determinants involved in the highly specific binding of Ras GTPase to its effectors, the conformational states of Ras in uncomplexed form and complexed to the downstream effectors Byr2, PI3Kγ, PLCε, and RalGDS were investigated using molecular dynamics and cross-comparison of the trajectories. The subtle changes in the dynamics and conformations of Ras up...

Many countries in 1995-2008 have experienced what we call the “valueadded erosion”, which describes the phenomenon of the decline in the sectoral shares of domestic value-added in a country’s exports as the country becomes more integrated into the Global Value Chains (GVCs). We argue that the decline of domestic value added share in a country’s exports is likely to be caused by the expansion of...

The adoption and diffusion of inputs in the production network is at the heart of technological progress. What determines which inputs are initially considered and eventually adopted by innovators? We examine the evolution of input linkages from a network perspective, starting from a stylized model of network formation. Producers direct their search for new inputs along vertical linkages, scree...

Many countries in 1995-2008 have experienced what we call “value added erosion”, which describes the phenomenon of the decline in the shares of domestic value added in a country’s exports as the country becomes more integrated into the Global Value Chains (GVCs). We argue that the decline of domestic value added share in a country’s exports is likely to be caused by the expansion of high value-...