In an earlier single-dose escalation study to evaluate the safety and pharmacokinetics of orally administered des-aspartate-angiotensin I (DAA-I) in healthy subjects, the plasma level of DAA-I could not be determined because DAA-I is rapidly degraded in the circulation. The present study investigated the oral bioavailability of DAA-I by measuring the prostaglandin E2 metabolite (PGEM) in the pl...

INTRODUCTION Sepsis is defined as an invasion of microorganisms and/or their toxins into the blood associated the reaction of the organism to this invasion. Severe sepsis is a major cost driver in intensive care medicine. In Germany, prevalence data was assessed in the context of the German Prevalence Study. Severe sepsis has a prevalence of 35% in German intensive care units. RESEARCH QUESTI...

BACKGROUND Direct acting antiviral agents (DAA) are highly effective yet expensive. Disparities by race and/or gender often exist in the use of costly medical advances as they become available. METHODS We examined a cohort of hepatitis C virus (HCV) patients who received care at the Veterans Administration facilities nationwide. We evaluated the effect of race and gender on DAA receipt after ...

Direct Anonymous Attestation (DAA) is one of the most complex cryptographic algorithms that has been deployed in practice. In spite of this, and the long body of work on the subject, there is still no fully satisfactory security definition for DAA. This was already acknowledged by Bernard et al. (IJIC’13) who showed that in existing models even fully insecure protocols may be deemed secure. Ber...

The present study investigated the action of des-aspartate-angiotensin I (DAA-I) on the pressor action of angiotensin II in the renal and mesenteric vasculature of WKY, SHR and streptozotocin (STZ)-induced diabetic rats. Angiotensin II-induced a dose-dependent pressor response in the renal vasculature. Compared to the WKY, the pressor response was enhanced in the SHR and reduced in the STZ-indu...

Each cotton fiber is a single cell that elongates to 2.5 to 3.0 cm from the seed coat epidermis within z 16 days after anthesis (DAA). To elucidate the mechanisms controlling this rapid elongation, we studied the gating of fiber plasmodesmata and the expression of the cell wall–loosening gene expansin and plasma membrane transporters for sucrose and K 1 , the major osmotic solutes imported into...

Each cotton fiber is a single cell that elongates to 2.5 to 3.0 cm from the seed coat epidermis within approximately 16 days after anthesis (DAA). To elucidate the mechanisms controlling this rapid elongation, we studied the gating of fiber plasmodesmata and the expression of the cell wall-loosening gene expansin and plasma membrane transporters for sucrose and K(+), the major osmotic solutes i...

Each cotton fiber is a single cell that elongates to 2.5 to 3.0 cm from the seed coat epidermis within z 16 days after anthesis (DAA). To elucidate the mechanisms controlling this rapid elongation, we studied the gating of fiber plasmodesmata and the expression of the cell wall–loosening gene expansin and plasma membrane transporters for sucrose and K 1 , the major osmotic solutes imported into...

Direct Anonymous Attestation (DAA) is a cryptographic protocol for privacy-protecting authentication. It is standardized in the TPM standard and implemented in millions of chips. A variant of DAA is also used in Intel’s SGX. Recently, Camenisch et al. (PKC 2016) demonstrated that existing security models for DAA do not correctly capture all security requirements, and showed a number of flaws in...

OBJECTIVE The aim of the study was to compare the dislocation rate between total hip arthroplasty (THA) via direct anterior approach (DAA) and via posterior approach (PA). METHODS We compared a consecutive series of 139 THAs via DAA with 177 THAs via PA. All study patients received ceramic-on-ceramic bearing surfaces and similar uncemented prostheses. Dislocation-free survival after THA was e...