Baclofen, particularly high-dose baclofen, has recently emerged as a treatment of major interest for alcohol-dependence. However, baclofen has many potentially dangerous side effects, and the maximal dose of baclofen that may be used is a matter of discussion. Here, the author analyses the medical charts of the last 100 patients seen in his clinic, 17 of whom have been taking a very high dose o...

Equity issues have led many economists to re-consider their preference for conducting efficiency analyses with aggregated estimates of the benefits and costs of changes in environmental resource allocations. For instance, there is evidence that health risks due to hazardous wastes disproportionately affects the poor and non-white. Policies that lead to these disproportionate effects are not nec...

PURPOSE Unsafe behaviors are an important cause of accidents in adolescent age groups. This study was designed to examine the behaviors of adolescent pedestrians in southern Iran. METHODS This is a descriptive analytical cross-sectional study. The study population consisted of high school students in Shiraz, capital city of Fars Province, Iran. Five hundred and sixteen students were selected ...

Explicitly coercive measures are sometimes necessary in the care and treatment of psychiatric patients. The author describes how use of such measures is not antithetical to patient-centered, recovery-oriented practice either in inpatient or outpatient settings. Citing a definition widely used by advocates to describe the overarching goal of recovery--"a full, meaningful, and self-determined lif...

Misoprostol, although originally introduced as a therapy for gastric ulcers, is now widely used in reproductive health. For some indications it is now the optimal choice, whilst for others it provides an important alternative, especially in low-resource settings. The optimal dose varies widely from 20 to 600 mcg depending on the indication and gestation. Use of the correct dose is important, to...

Ionizing radiation has many practical applications, but it is also, as it is well known, dangerous to human health. The purpose of this study was to estimate the dose and exposure for medical staff involved in sentinel node assay and to determine how safe this assay really is. The theoretical method was used for calculation. Three groups of medical staff were selected: nuclear medicine speciali...

Few risk factors for nonsuicidal self-injury (NSSI) have been identified. This study investigated diminished aversion toward self-injury (i.e., NSSI, suicide/death stimuli) and self-criticism as unique NSSI risk factors. After terminating a treatment study, 154 adults with a recent and frequent NSSI history completed self-report and computer-based measures of psychopathology, implicit and expli...

BACKGROUND The Prostate cancer is the 2nd most common cancer worldwide for males, and the 5th most common cancer overall, with an estimated 900,000 new cases diagnosed in 2008 (14% of the total in males and 7% of the total overall) aim of this study was to assess some of the most proposed environmental factors influencing the incidence of prostate cancer among Iranian men. Smoking, opioids, occ...

Background The number of involuntary admissions in the Netherlands increased from 40 per 100,000 citizens in 1997 to 48 in 2005. During this period the mental health law did not change. In the Netherlands patients can be involuntarily admitted if they have a mental disorder causing dangerous behavior. One of the reasons for the increase in commitments may be that there is a shift in dangerousne...