Deep brain stimulation (DBS) has provided remarkable benefits for people with a variety of neurologic conditions. Stimulation of the ventral intermediate nucleus of the thalamus can dramatically relieve tremor associated with essential tremor or Parkinson disease (PD). Similarly, stimulation of the subthalamic nucleus or the internal segment of the globus pallidus can substantially reduce brady...

Electrical stimulation of the basal ganglia [e.g., the same structure that demonstrates abnormal physiology in Parkinson’s disease (PD) patients] relieves many of the motor symptoms of the disease. The treatment involves the placement of a permanent electrode in the basal ganglia as well as of a brain pacemaker that is placed under the skin of the chest and provides the power needed to produce ...

Deep-brain stimulation (DBS) is a clinical intervention that has provided remarkable therapeutic benefits for otherwise treatment-resistant movement and affective disorders. The resulting direct causal manipulation of both local and distributed brain networks is not only clinically helpful but can also help to provide novel fundamental insights into brain function. In particular, DBS can be use...

Innovations in the field of deep brain stimulation (DBS) are introduced recently, considering that the fundamentals of DBS remained significantly unchanged over 25 years. Technological advances involve not only DBS hardware but also new patterns of stimulation, brain imaging and pathophysiological pathways. Every effort is done to obtain the best outcome for the patient with the lower adverse e...

Deep Brain Stimulation Chikashi FUKAYA, Kazutaka KOBAYASHI, Hideki OSHIMA, Takamitsu YAMAMOTO and Yoichi KATAYAMA Neuromodulation Center, Nihon University Hospital Department of Neurological Surgery and Division of Applied System Neuroscience, Nihon University School of Medicine Deep brain stimulation (DBS) is an important component of the therapy for movement disorders and intractable pain. In...

Deep brain stimulation (DBS) has provided remarkable therapeutic benefits for people with a variety of neurological disorders. Despite the uncertainty of the precise mechanisms underlying its efficacy, DBS is clinically effective in improving motor function of essential tremor, Parkinson’s disease and primary dystonia and in relieving obsessive-compulsive disorder. Recently, this surgical techn...