Introduction: Deep brain stimulation (DBS) is used to treat Parkinson's disease (PD), when medical therapies are not efficient enough [1]. DBS requires the implantation of stimulation electrodes reaching into deep brain areas, commonly into the subthalamic nucleus (STN) that is one of the relay of the extrapyramidal circuit. Electrical pulses are sent on a fixed regular pace. Despite the proven...

Deep brain stimulation (DBS), applying high-frequency electrical stimulation to deep brain structures, has now provided an effective therapeutic option for treatment of various neurological and psychiatric disorders. DBS targeting the internal segment of the globus pallidus, subthalamic nucleus, and thalamus is used to treat symptoms of movement disorders, such as Parkinson's disease, dystonia,...

Deep brain stimulation (DBS), applying high-frequency electrical stimulation to deep brain structures, has now provided an effective therapeutic option for treatment of various neurological and psychiatric disorders. DBS targeting the internal segment of the globus pallidus, subthalamic nucleus, and thalamus is used to treat symptoms of movement disorders, such as Parkinson’s disease, dystonia,...

stimulation permits routine EKG, EEG, and polysomnography Abstract—As the population of patients treated with deep brain stimulation (DBS) grows and the patients age, more will require routine or emergent electrophysiologic tests. DBS artifact may render these uninterpretable, whereas stopping DBS may release symptoms that confound evaluation. The authors find that monopolar, but not bipolar, s...

Background: In Parkinson’s disease, deep brain stimulation (DBS) of the subthalamic nucleus (STN) or globus pallidus internus (GPi) produces comparable motor benefits. Although both increases risk cognition and verbal fluency (VF) decline, is greater following STN-DBS. The consequences stimulating these different sites on network activity unknown. We use functional magnetic resonance imaging (f...

Abstract Deep brain stimulation has become a last resource procedure for severe, chronic and refractory OCD. However, the is highly invasive its efficacy must be balanced against risks it may entail. In addition, there are number of procedure-related issues that influence DBS, such as target stimulation, parameters to selected, presence comorbidities exclusion criteria, or in different OCD subt...

Obsessive-compulsive disorder (OCD) is a psychiatric disorder manifested by thoughts and impulses that produce anxiety and result in patients performing repetitive rituals. Treatment generally consists of cognitive behavioral intervention and serotonin reuptake inhibitors. Up to 40% of patients will have functional impairment that significantly affects their quality of life. In the late 1990’s,...

The vision behind our project is a closed-loop system for continuous deep brain stimulation (DBS) based on features extracted from complex motion data. Our focus is on Parkinsons Disease (PD) patients, with a possible expansion to related neurological disorders. The system we envision is lightweight, will continuously gather motion information, will automatically extract high-level features fro...

Essential vocal tremor (EVT) is the presence of a tremulous voice that is commonly associated with essential tremor. Patients with EVT often report a necessary increase in vocal effort that significantly worsens with stress and anxiety and can significantly impact quality of life despite optimal medical and behavioral treatment options. Deep brain stimulation (DBS) has been proposed as an effec...