The simulation of protein folding kinetics is a challenging task and modern computers are just reaching the performance levels required to push multiple folding trajectories into the microsecond range. Even with enough computing power at hand, the verification of the simulated protein kinetics usually relies on static parameters like average folding rates from folding experiments[34]. In recent...

The double exponential model (DEM), or Laplace distribution, is used in various disciplines. However, there are issues related to the construction of confidence intervals (CI), when using the distribution.In this paper, the properties of DEM are considered with intention of constructing CI based on simulated data. The analysis of pivotal equations for the models here in comparisons with pivotal...

This paper describes the architecture of high performance, particle simulation machine, DEM-1 for short-range particle interaction computations. All existing particle simulation machines have specialized pipelines to calculate long-range particle interactions effectively. However, their ability to perform particle simulations efficiently diminishes with short-range interactions. The communicati...

A hydrologically correct digital elevation model (DEM) forms a basis for realistic environmental modelling, especially in complex terrain. We have performed a study in the Coarse Sandy Hilly Catchments (CSHC) of the Loess Plateau, China, which demonstrates pragmatic, yet effective methods for improving the quality of the DEM by: (1) identifying and correcting source topographic data errors and ...

Discrete element modeling is being used increasingly to simulate flow in fluidized beds. These models require complex measurement techniques to provide validation for the approximations inherent in the model. This paper introduces the idea of modeling the experiment to ensure that the validation is accurate. Specifically, a 3D, cylindrical gas-fluidized bed was simulated using a discrete elemen...

In this paper we discuss about the need of a new DEM representation for simulation in GIS. This leads us to analyse through quality criteria the current DEM structures. Then we propose a new DEM representation adapted for spatial and graph terrain analysis. An algorithm is presented and the qualities of this structure are analysed. Finally, this structure is used in a thematic application for a...

Recently software libraries known as physics engines have begun to gain interest within the computing communities. They are designed primarily for use within the computer game industry but also currently find credence within real-time animation and robotics simulation. The technical requirements of a Discrete Element Model (DEM) are markedly similar to that of a gaming rigid body problem. A DEM...

This study evaluates the quality of the Advanced Spaceborne Thermal Emission Radiometer-Global Digital Elevation Model version 2 (ASTER GDEM2) in comparison with the previous version (GDEM1) as well as the Shuttle Radar Topographic Mission (SRTM) DEM and topographic-map-derived DEM (Topo-DEM) using inundation area analysis for the projected location of the Karian dam, Indonesia. In addition, th...

Within Computer Science, reusability of specific modular software components is generally accepted as best practice. Simulation techniques such as Discrete Element Modelling (DEM) rely on the well defined problems of Newtonian physics, and while differences exist in the methods defined to compute solutions to these problems, each method follows the same basic set of premises. Recently, librarie...