It is a challenge for dentists to save dental pulp in patients with pulp disease without resorting to root canal therapy. Formation of tertiary dentin to maintain pulp vitality is a key odontoblast response to dental pulp injury. Vascular endothelial growth factor (VEGF) is the most potent angiogenic and vasculogenic factor involved in tertiary dentin formation. It was hypothesized that VEGF ma...

• If the pulp chamber of a tooth is penetrated, either by dental caries, or by a dental drill, inflammation and eventual death of the pulp tissue usually follows. While a long interval may elapse before degeneration is complete, necrosis is an almost inevitable consequence of pulpal penetration. A current explanation in the dental literature for this phenomenon is as follows. The application of...

Dens invaginatus is a developmental anomaly that results in an invagination of the enamel organ into dental papilla prior to calcification tissues. Apical fenestration defined as defect which apices perforate mucosa and are exposed oral cavity. These anomalies require multidisciplinary management order give better prognosis patient, since it acts retentive area biofilm, affecting deteriorating ...

Endodontic regeneration shows promise in treating dental pulp diseases; however, no suitable scaffolds exist for pulp regeneration. Acellular natural extracellular matrix (ECM) is a favorable scaffold for tissue regeneration since the anatomical structure and ECM of the natural tissues or organs are well-preserved. Xenogeneic ECM is superior to autologous or allogeneic ECM in tissue engineering...

Class II major histocompatilibity complex (MHC)-expressing cells are usually distributed in dental pulp, and it was postulated that the colony-stimulating factor (CSF) derived from dental pulp fibroblasts contributes to the migration of class II MHC-expressing cells into pulp tissue. This study aimed to investigate the CSF production of human dental pulp fibroblasts. In pulp tissue sections, gr...

Different types of radiographs of dental structures undoubtedly offer a least destructive approach to age estimation of individuals, but most of these methods are based on the calcification stages of the developing teeth. Very limited studies have been carried out in India using Kvaal’s technique based on pulp changes on radiographs as a tool for age estimation. Further, only few studies have b...

 Dental Pulp Stem Cells (DPSCs) can be found within the cell rich zone of dental pulp. These stem cells, under specific stimuli, differentiate into many cell types which have wide therapeutic applications.   The dental stem cells are derived from both deciduous and permanent teeth. The viable dental stem cells are very simple to collect, without any mortality and morbidity. Dental pulp stem c...

Esterase activity of the dental pulp has been iernonstrated by histochemical technics on tissue sections by Burstone (Calcification in Biological Systeins, 1960, p. 232) and by Yoshiki (Butt. Tokyo Dent. Coll., 3:14-28, 1962). Aside from the localization of cholinesterases in the human dental pulp by Avery and Rapp (Stain Technol., 33:31-7, 1958) and by Ten Cute and Shelton (Arch. Oral Biol., 1...

BACKGROUND Pulp stones are discrete calcified bodies found in the dental pulp. The aims of this study were to calculate the prevalence of pulp stones in young Australian adults using radiographs, and to report any associations between occurrence of pulp stones and sex, tooth type, dental arch, side and dental status. METHODS From 217 undergraduate dental students, comprising 123 males and 94 ...