objective(s): sertoli cells support in vivo germ cell production; but, its exact mechanism has not been well understood. the present study was designed to analyze the effect of sertoli cells in differentiation of mouse embryonic stem cells (mescs) to germ cells.   materials and methods: a fusion construct composed of a stra8 gene promoter and the coding region of enhanced green fluorescence pro...

background: cell-based treatments are currently being actively received great attention among scientists and clinicians for a variety of diseases as well as diabetes .the aim of this study was to investigate the effect of allotransplantation of fetal liver-derived cell suspension in patients with type 1 diabetes. methods: patients with type 1 diabetes (n=16) aged 6-30 years-old were included in...

background: although cervical cancer mortality has reduced during last years, but it is still leading cause of mortality among women. many efforts have performed to develop new drugs and strategy to cure cervical cancer. mesenchymal stem cells (mscs) have many advantages that make them a suitable choice as a cell therapeutic agent in cancer treatment. there are different transfection methods fo...

Stem cell-based therapy has great potential in treating health conditions including cardiovascular, autoimmune, type I diabetes, neurodegenerative and bone and cartilage diseases also in spinal cord injuries, malformations and cancer. In addition to their potential use to treat systemic diseases, stem cell-based therapy also provides a powerful tool to treat oral and dental diseases such as cra...

arm grooves of star-fish have mesenchymal stem cells derived from adipose tissue cell. widespread studies have shown that stem cells derived from adipose-derived mesenchymal stem cell from bone marrow have many similarities in terms of the ability to differentiate into a variety of tissues. most of the animals live in warm and shallow waters and the waters of this feature is that it is low in d...

introduction: lactate dehydrogenase is one of the cardiac enzyme markers, studied in vivo. in the present study, activity and kinetic properties of enzyme extracted from cardiomycytes derived from mouse embyronic stem cell in vitro were compared with enzyme extracted mouse neonatal from cardiomyocytes in vivo. material and methods: mouse embryonic stem cells were cultured and differentiated and...

background: although the pathogenesis of diabetes type 1 (t1d) is not fully elucidated. different clusters of lymphocytes such as cd4+ and cd8+ t cells are involved in it. moreover, the mechanism of how stem-cell therapy results in significant therapeutic outcomes in diabetes remains obscure. in the current study, we aimed to analyze lymphocyte subsets in patients with t1d before and after trea...

Arm grooves of star-fish have mesenchymal stem cells derived from adipose tissue cell. Widespread studies have shown that stem cells derived from adipose-derived mesenchymal stem cell from bone marrow have many similarities in terms of the ability to differentiate into a variety of tissues. Most of the animals live in warm and shallow waters and the waters of this feature is that it is low in d...

objective(s) some investigation has indicated that adipose-derived stem cells possess different surface epitopes and differentiation potential according to the localization of fat pad from which the cells were derived. in the present study proliferation capacity and aging of such cells were explored. materials and methods adherent cells were isolated from the collagenase digests of adipose tiss...