Methods We realized a 2 years ambispective study for assessment safety and efficacy of subcutaneous immunotherapy with a dust mite vaccine with the adjuvant L-tyrosine. We reviewed the data of 292 patients with allergic rhinitis and/or asthma. They are sensitized to Dermatophagoides pteronyssinus or Dermatophagoides farinae and or Blomia tropicallis. A data base was constructed to allow complet...

Background House dust mites (HDM), including Dermatophagoides pteronyssinus (Dpt) and Dermatophagoides farinae (Df), are one of the commonest aeroallergens worldwide eliciting allergic manifestations [1]. Allergenic phenomenon is tightly associated both with the mites themselves and with ligands derived from mite-associated bacterial/fungal products. Some Dpt allergens belong of lipid-binding p...

Background House Dust Mites are important etiological agents of respiratory allergy. Allergen mixtures are often used for specific immunotherapy in polysensitized patients, although scientific evidence to support its efficacy, safety and stability is scarce. Sublingual immunotherapy (SLIT) is being gradually accepted as an alternative to conventional subcutaneous immunotherapy. For SLIT, higher...

Twenty-five patients with perennial rhinitis and a positive skin prick test (SPT) for Dermatophagoides pteronyssinus (Dp) and Dermatophagoides farinae (Df) were submitted to nasal provocation and the radioimmunosorbent test (RAST) for specific IgE-antibodies. We found a significant correlation in the reaction to both allergen extracts for all parameters examined. In addition, there was a signif...

The mite Dermatophagoides pteronyssinus has been identified in dust from the houses of children in Birmingham suffering from asthma. Skin tests were carried out on 150 asthmatic children with extracts of D. pteronyssinus, of the related species D. farinae, of other mites found in house dust, and of crude house dust. Though positive reactions to D. pteronyssinus were obtained more frequently and...

Of 100 asthmatic patients prick tested for allergy to Dermatophagoides pteronyssinus, 88% were positive compared with only 14% of controls. A significantly greater proportion of dust samples from the houses of the asthmatics contained Dermatophagoides mites. The house-dust mite D. pteronyssinus, constituted 90% of the mites identified, other pyroglyphid mites, Cheyletus and Glycophagus making u...

Background The house dust mites are cosmopolitan guest in human habitation. Dust mites occur in nearly all homes. They are generally found in pillows, bed sheets, mattress, stuff toys, carpets etc. Dust mites feed on organic detritus such as flakes of shed human skin and flourish in stable environment of dwellings. Exposure to house dust mites is recognized as major cause allergy worldwide. The...

Methods Our prospective study included eighty-eight asthmatic children, with ages between 1 and 18 years, who were admitted to the Clinic of Pediatrics I from Târgu Mureş, Romania, between October 2008 and June 2010. We analyzed the age, month of birth, sensitization to a given antigen (Dermatophagoides pteronyssinus, Dermatophagoides farinae, milk proteins, egg, mold, dog epithelium, cat epith...