In this research, we model a semiconductor wafer fabrication process as a complex job shop, and adapt a Modified Shifting Bottleneck Heuristic (MSBH) to facilitate the multi-criteria optimization of makespan, cycle time, and total weighted tardiness using a desirability function. The desirability function is implemented at two different levels of the MSBH: the subproblem solution procedure leve...

A physicochemical property-based desirability scoring scheme for fragment-based drug discovery was developed for class A aminergic GPCR targeted fragment libraries. Physicochemical property distributions of known aminergic GPCR-active fragments from the ChEMBL database were examined and used for a desirability function-based score. Property-distributions such as log D (at pH 7.4), PSA, pKa (str...

Two studies examined folk concepts of the good life. Samples of college students (N = 104) and community adults (N = 264) were shown a career survey ostensibly completed by a person rating his or her occupation. After reading the survey, participants judged the desirability and moral goodness of the respondent's life, as a function of the amount of happiness, meaning in life, and wealth experie...

This work presents a multiple objective linear programming (MOLP) model based on the desirability function approach for solving the aggregate production planning (APP) decision problem upon Masud and Hwang’s model. The proposed model minimises total production costs, carrying or backordering costs and rates of change in labor levels. An industrial case demonstrates the feasibility of applying t...

Thermal stability and Surface hardness of the super-finished surface is a very important aspect to preserve texture workpiece in MAF process. In this present study, multi-objective optimization EN-31 finished through “Increase Temperature” Hardness” are considered for diminish their impact on EN-31. work Desirability function analysis (DFA) has been used optimize desired responses Experiments w...