The effects of standardized exercise training and detraining on the content of cholesterol, triglyceride, and nitrogen in blood, myocardium, skeletal muscle, and epididymal fat of rats were studied. Forty-eight 90-day-old male rats were randomly assigned to four groups (two control groups, one trained group, and one trained and detrained group). Trained rats were subjected to 8 weeks of moderat...

OBJECTIVE To evaluate the effects of short-term exercise detraining on the functional fitness of older women after a 12-week water-based exercise (WE) program. METHODS Healthy older women (trained (TR) group) were submitted to 12 weeks WE (three 45 min sessions per week) followed by a 6-week detraining period. A group of aged-matched women without any exercise training (UN group) were evaluat...

Expiratory muscle strength training (EMST) is efficacious for improving maximum expiratory pressure (MEP), cough function, and swallowing safety in Parkinson disease (PD). However, there are no published reports describing detraining effects following EMST in persons with PD. Moreover, there are no published reports describing detraining effects following any behavioral swallowing intervention....

Intramuscular signaling and glucose transport mechanisms contribute to improvements in insulin sensitivity after aerobic exercise training. This study tested the hypothesis that increases in skeletal muscle capillary density (CD) also contribute to exercise-induced improvements in whole-body insulin sensitivity (insulin-stimulated glucose uptake per unit plasma insulin [M/I]) independent of oth...

FAULKNER, JOHN A., LEO C.MAXWELL, AND DAVID A. LIEBERMAN. Histochemical characteristics of muscle Jibers from trained and detrained guinea pigs. Am. J. Physiol. 222(4) : 836-840. 1972.~Sixweek-old guinea pigs have nearly 12,000 fibers per plantaris cross section. With aging, some 2,700 fibers were lost. Daily endurance running prevented the loss of fibers and fibers were smaller. Trained animal...

One of the diagnostic criteria in order to differentiate between physiological and pathological left ventricular hypertrophy is the wall thickness reduction after at least 3-month detraining period, which is considered a marker of the athlete's heart. This report describes detraining-related regression of LV hypertrophy and improvement in myocardial deformation in a junior athlete likely to hav...

The present study aimed to investigate the impact of a 1-month detraining composed by Christmas and New Year's Day in the functional and cognitive parameters of 12 older women who had previously participated in 22-week moderate intensity strength training program (ST; n=6) or remained performing their regular habits of life during all study period, without engaging in physical exercise programs...

This study examined the effect of aerobic training on leg strength, power, and muscle mass in previously sedentary, healthy older men (70-80 yr). Training consisted of 30-45 min of cycle ergometry at 50-70% maximal oxygen consumption (VO2max), 3 times weekly for 16 wk, then 4 wk detraining, or assignment to a nontraining control group (n = 12 both groups). Training increased leg strength, leg p...

PURPOSE The purpose of this study was to identify the effect of detraining on motor unit potential area (SMUP), muscular function and physical performance, according to CNTF gene polymorphism. METHODS For this study, GG (normal homozygote, n = 8) group and GA + AA (mutation heterozygote and homozygote, n = 10) group were divided by CNTF gene polymorphism and both groups were performed detrain...

Regular exercise may improve systemic markers of chronic inflammation, but direct evidence and dose-response information is lacking. The objective of this study was to examine the effect and time course of changes in markers of chronic inflammation in response to progressive exercise training (and subsequent detraining). Forty-one sedentary men 45-64 yr of age completed either a progressive 24-...