objective: foot ulcer in diabetic people has a negative effect on their quality of life. it can decrease social activities, and increase stress. it can also limit doing job tasks, and increase life financial burden and high medical expenses. so examination of feet and considering foot care in these patients are essential. materials and methods: this analytic-descriptive research was performed o...

background bioflavonoids are well known for their multi directional biologic activity including antidiabetic effect. it has been demonstrated that flavonoids can act as insulin secretagogue or insulin mimetic agents. objectives this experimental study was designed in arak university of medical sciences, arak, iran, to investigate the effects of biochanin a (a bioflavonoid) on fasting blood gluc...

objective: crocinisa saffron constituent with a potent anti-oxidant activity. the present study investigated the effects of crocin and insulin treatments (alone or in combination) on cardiac function and pathology in diabetic rats. materials and methods: diabetes was induced by intraperitoneal (i.p.) injection of streptozotocin (stz, 50 mg/kg). thereafter, crocin (5, 10 and 20 mg/kg, i.p.), sub...

purpose: to study recordings of oscillatory potentials (ops) of the electroretinogram (erg) in diabetic eyes that have no visible fundus alterations, to ascertain whether changes in sensitivity are evident when compared with recordings from age-matched controls. methods: ops of the erg were measured from 68 eyes of 34 patients with diabetes without retinopathy and from 30 eyes of 15 normal subj...

objective: stress and cortisol increase blood glucose. considering the role of central catecholaminergic pathways on hypothalamic-pituitary adrenocortical axis, and results of some studies that alprazolam (a benzodiazepine) has inhibitory effect on catecholamines, it seems that alprazolam may reduce blood glucose. the aim of this study was to evaluate the effect of alprazolam on serum insulin l...

diabetes mellitus is the most common cause of chronic renal disorders and end-stage kidney disease in developed countries. it is the major cause of dialysis and transplantation. failure in renal function causes wide disorders in the body. diabetes results in wide range of alterations in the renal tissue. it is believed that early histological changes in diabetic nephropathy are detectable 2 yea...

diabetes mellitus is a group of metabolic diseases caused by a combination of insulin resistance and impaired insulin secretion by pancreatic β cell. in 2007, 246 million people (roughly 6%) were affected by diabetes worldwide and it is estimated that this will increase to 380 million in 2025. diabetes is associated with several long-term complications such as cardiovascular disease, nephropath...

background: epidemiological characteristics of diabetic foot infection in our region are not clear. the purpose of this study was to determine the epidemiological features of diabetic foot infection in babol, north of iran. methods: from march, 2005 to april, 2010, the epidemiological features of 450 cases of diabetic foot infection treated in two main teaching hospitals of babol medical univer...

background: diabetes mellitus is the most common metabolic disorder with many complications such as neuropathic pain which relief from it is a dilemma. objectives: to investigate the effect of hydroethanolic extract of rubus fruticosus on neuropathic pain in diabetic rats. materials and methods: in this experimental case –control study, forty eight male wistar rats (250±20 g) were divided rando...

introduction: diabetes mellitus is a global public health issue that has a prevalence of between 5-8% in different parts of iran. one of the most serious complications of diabetic foot ulcer and chronic complications of diabetes mellitus is one of the leading causes of morbidity and amputation in patients with diabetes. on the other hand, amputations in patients with diabetes are three-year sur...