Duodenal bile from 27 diabetes was compared with samples from healthy subjects matched for age, sex, and body mass index. Cholesterol saturation and the molar percentages of bile acids, phospholipids, and cholesterol were not significantly different. Most bile samples were supersaturated in both groups. The maturity onset diabetics who were almost all obese had more saturated bile than the slim...

the epidemic of obesity and associated features of metabolic syndrome including NASH (non-alcoholic steatohepatitis) and NAFld (non-alcoholic fatty liver disease) is spreading worldwide; thanks to the increasingly sedentary life style! it is estimated that 12-15% of the global population is affected with NAFld; 50% of diabetics develop NAFld. it is seen in 57-74% of obese persons and the preval...

Background: Leptin is an important adipokine hormone released from adipose tissue which is associated with obesity and diabetes in different populations. Objective: To investigate the serum leptin concentrations for its correlation with diabetes, obesity and gender in a small population from Faisalabad, Pakistan. Methods: From our sample collection of more than 500 subjects for metabolic disord...

The most important objectives of this presentation are to attract attention that the associations between oral anti-diabetics drugs and statin at the categories of patients with type 2 obese diabetes mellitus and dyslipidaemia, is dangerous. We know that diabetic patient’s type 2 obese needs diet and oral antidiabetics drugs (biguanide or combination between biguanide and sulfonylurea) to maint...

It is a universal endocrine disorder and both its incidence and prevalence are alarmingly increasing day by day. Leptin is a hormone communicating information on the body fat store or energy reserve to the brain, thus maintaining normal functions of several neuro endocrine axis. Obesity, eating disorder (Anorexia Nervosa and Bulimina Nervosa) is associated with altered serum leptin. Leptin leve...

Skin disorders are common in diabetic patients and may also act as clues for diagnosis in undiagnosed cases. These manifestations may be summarized in five categories including non-infectious, infectious, treatment-related and miscellaneous manifestations as well as diabetic foot ulcer. The most common non-infectious disorder occurring in up to 70% of patients is diabetic dermopathy. Infectio...

Diabetes mellitus, a major health concern throughout the world, is often coexisting with obesity, hypertension and dyslipidemia. Several studies have shown that dyslipidemia and hypertension are the major two contributing risk factors of CVD. But interplay among them still to be elucidated. So the present study was aimed to evaluate the lipid abnormalities among hypertensive-overweight to obese...

Currently there is little doubt that the body mass index ( BMI) is not an appropriate tool to grant access to metabolic surgery, especially in type 2 diabetics (T2D). Several studies are pointing towards other parameters that should go along with BMI in the treatment decision tree in non morbidly obese diabetics. Insulin resistance, fat distribution among others are considered good tools to pre...