Accumulating evidence indicates that diaphragmatic weakness is common and frequently severe in mechanically ventilated patients. Supinski and Callahan now report that infection is a major risk factor for diaphragmatic weakness in this patient population. Importantly, they show that patients with the greatest levels of diaphragmatic dysfunction have a much poorer prognosis in terms of more prolo...

Incidence Congenital diaphragmatic hernia (CDH) refers to a congenital defect in the posterolateral diaphragm at the “foramen of Bochdalek.” It is a relatively common cause of neonatal respiratory distress with an overall incidence between 1:2000 and 1:5000 live births. CDH accounts for about 90% of congenital diaphragmatic defects. Eighty to ninety percent of congenital diaphragmatic hernias o...

BACKGROUND Traumatic diaphragmatic ruptures affect mainly the left side. In an experimental study in human corpses we examined the stretch behaviour of the left and right diaphragmatic halves. METHODS In a total of 8 male and 8 female corpses each diaphragmatic half was divided into 4 different segments. Each segments stretch behaviour was investigated. In steps of 2 N the stretch was increas...

conclusions a high index of suspicion is essential for early detection of ddr and dddr. patients with high impact injuries or surrounding organ damage should be followed with serial clinical examinations, follow-up radiologic assessments, and even re-exploration in situations highly suspicious for diaphragmatic injuries. introduction diaphragmatic rupture (dr) is an uncommon, potentially seriou...

objectives: the aim of this study was to evaluate the surgical approach in post traumatic diaphragmatic hernia. methods: this prospective cross-sectional study was conducted in the department of cardiovascular and thoracic surgery, sher-i- kashmir institute of medical sciences (skims), kashmir, india. we included all patients with post traumatic diaphragmatic hernia undergoing operation in our ...

BACKGROUND Diaphragmatic injuries occur in 0.8-8% of patients with blunt trauma. The clinical diagnosis of diaphragmatic rupture is difficult and may be overshadowed by associated injuries. Diaphragmatic rupture does not resolve spontaneously and may cause life-threatening complications. The aim of this study was to present radiological findings in patients with diaphragmatic injury. MATERIAL...

Mechanical ventilation (MV) is associated with diaphragmatic oxidative stress that contributes to both diaphragmatic atrophy and contractile dysfunction. However, the pathways responsible for oxidant production in the diaphragm during MV remain unknown. To address this issue, we tested the hypothesis that diaphragmatic nitric oxide synthase (NOS) activity is elevated during MV, resulting in nit...

BACKGROUND Pompe disease is a progressive metabolic myopathy. Involvement of respiratory muscles leads to progressive pulmonary dysfunction, particularly in supine position. Diaphragmatic weakness is considered to be the most important component. Standard spirometry is to some extent indicative but provides too little insight into diaphragmatic dynamics. We used lung MRI to study diaphragmatic ...

BACKGROUND Although real time ultrasonography has been used in the last decade to record diaphragmatic motion, the relation between diaphragmatic excursion and different inspired volumes (VT) has not been assessed by ultrasound. METHODS Ten normal subjects were studied in the supine posture. Diaphragmatic excursion and VT were assessed simultaneously by M mode ultrasonography and respiratory ...