BACKGROUND Chronic watery diarrhoea is one of the most common symptoms prompting GI evaluation. Recently, new diagnostic considerations have emerged as possible factors in chronic diarrhoea. AIM To review available data regarding diagnosis and treatment of chronic diarrhoea with an emphasis on bacterial overgrowth and bile acid malabsorption. METHODS A systematic search of the English langu...

Persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in Nigeria. Hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of P. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in Wistar rats to substantiate this claim. The chloroform and met...

INTRODUCTION Diarrhoea diseases remain a major public health threat with nearly 1.7 billion cases annually worldwide occurring in all age groups. In Ghana diarrhoea kills about 14,000 children under five years annually. We therefore analysed data to determine the morbidity pattern of diarrhoea diseases in the Central Region of Ghana. METHODS Health facility morbidity data was reviewed from 20...

Persistent diarrhoea is an important cause of illness and death in children in developing countries. Moreover, as acute diarrhoea is more widely and successfully treated with oral rehydration therapy (ORT), the proportion of diarrhoea deaths associated with persistent diarrhoea will probably increase. In the mid1980s the World Health Organization recognised that efforts to control persistent di...

Diarrhoea is one of the childhood diseases that result to high mortality. Despite World Health Organization (WHO) recommendation combination treatment regimen oral rehydration salts (ORS) and zinc supplements for management this disease, it effectiveness in treating preventing reoccurrence diarrhoea among under-five children remains a serious concern. Therefore, main objective study was assess ...

Diarrhoea after renal transplantation is not an uncommon problem [1]. We present the case of a 61-year-old renal transplant recipient on mycophenolate mofetil (MMF) and steroids who presented with chronic diarrhoea and substantial weight loss. The diarrhoea was ascribed to MMF and the patient was converted to enteric-coated mycophenolic sodium (EC-MPS), without effect. Comprehensive workup reve...

Bitar, J., Najjar, S. S., and Asfour, R. Y. (1970). Archives of Disease in Childhood, 45, 190. Diphenoxylate hydrochloride therapy in the diarrhoea of malnourished infants. In a double-blind study on 45 malnourished infants with moderately severe non-specific diarrhoea, diphenoxylate hydrochloride proved to be an effective antidiarrhoeal agent when the diarrhoea was acute, but not as effective ...

Clostridium difficile can cause inflammatory diarrhoea and colitis by disrupting normal colonic flora. Corticosteroids are effective against diarrhoea associated with inflammatory bowel disease, but their effectiveness in treating inflammatory diarrhoea of C difficile has not been reported. In this preliminary report, we describe the use of corticosteroids in a child with severe C difficile dia...