The presence of pharmaceutical compounds and their metabolites in aquatic systems has become a concern in the past few years due, in part, to their ubiquity in the environment. However, at present, the persistence and ecotoxicity of many of these compounds remains unknown. Clofibric acid is the active metabolite of clofibrate, a lipid regulator. It is detected in most aquatic systems where phar...

This paper describes the Brimstone Farm dataset used for the comparison of pesticide leaching model performance. The tasks set to the modellers are then described. The soil of the site is heavy clay, in which cracks have a major effect on the hydrology. Data are presented for the leaching of isoproturon and mecoprop from two contrasting plots. Contrasting soil moisture states, resulting from di...

STUDY OBJECTIVE Data on poisoning with MCPA (4-chloro-2-methyl-phenoxyacetic acid) are limited to 6 case reports. Our objective is to describe outcomes from intentional self-poisoning with MCPA in a prospective case series of 181 patients presenting to hospitals in Sri Lanka. METHODS Patient information was collected by on-site study physicians as part of an ongoing prospective cohort study o...

Organo-clay complexes in soil play an important role in the immobilization and persistence of xenobiotics. In this study, the fate of 14 C-labeled 4-(3,5-dimethylhept-3-yl)phenol (NP) and 4-chloro-2mehtylphenoxyacetic acid (MCPA) in soil was examined using incubation periods from 1d to 180d (NP) and 1d to 120d (MCPA). Special emphasis was on the distributions of the compounds and its degradatio...

Sphingomonas sp. strain ERG5 was isolated from a bacterial community, originating from a groundwater aquifer polluted with low pesticide concentrations. This bacterium degrades 2-methyl-4-chlorophenoxyacetic acid (MCPA) in a wide spectrum of concentrations and has been shown to function in bioaugmented sand filters. Genes associated with MCPA degradation are situated on a putative conjugative p...

What information is represented in the interactions between neural populations is unknown due to the lack of multivariate methods for decoding the representational content of neural communication. Here we present Multi-Connection Pattern Analysis (MCPA), which probes the involvement of distributed computational processing and probe the representational structure of neural interactions. MCPA lea...

Two methods for the quantitative analysis of 2,4-dichlorophenoxyacetic acid (2,4-D) and 2-methyl-4-chlorophenoxyacetic acid (MCPA) in urine were compared. The first was an high-performance liquid chromatography method using a C8 column with ion suppression and diode array detection. The urine extracts were first purified by solid-phase extraction (SPE) on silica capillary columns. The detection...

The performance and feasibility of switched multibeam array antennas in cellular systems is investigated. We assume that multicarrier power amplifiers (MCPA:s) are used in the base-station, to co-amplify the transmitted signals. The MCPA generates intermodulation distortion and it is shown how the multibeam antenna makes the radiated intermodulation distortion dependent on the azimuthal lookdir...

The objective of this study was to identify the main sources of variation in pesticide losses at field and catchment scales using the dual permeability model MACRO. Stochastic simulations of the leaching of the herbicide MCPA (4-chloro-2-methylphenoxyacetic acid) were compared with seven years of measured concentrations in a stream draining a small agricultural catchment and one year of measure...

OBJECTIVES The aim of the present project was to assess population exposure to pesticides in the vicinity of pesticide dump sites and make a preliminary evaluation of the potential health hazards to humans. MATERIALS AND METHODS Of the 286 pesticide dump sites registered in Poland, 40 were selected as the largest source of ecological hazard. The application of the Hazard Ranking System made i...