Salivary gland involvement is one of the radioiodine therapy complications. Salivary gland scintigraphy in quantitative mode can accurately evaluate salivary gland function. Methods: Salivary gland scintigraphy was performed with Tc-99m Pertechnetate, at the time of iodine therapy as a basic study and then 3 weeks and 3 months afterwards. Ejection Fraction (EF) of parotid and submandibula...

Introduction. Thyroid cancer is one of the most common malignant neoplasms endocrine system. well-differentiated thyroid constitutes about 90 % all tumors gland. Despite growing morbidity and high incidence this pathology, in case timely diagnosis treatment has favorable prognosis. Aim. using clinical examples, to demonstrate possibility thyroglobulin measurement needle washouts fineneedle aspi...

background: the aim of this study was to understand any association between differentiated thyroid carcinoma (dtc) and ile3434thr xrcc7 gene polymorphism (genbank accession number: rs7830743). dtc is the most prevalent thyroid neoplasm, which includes papillary and follicular cell carcinoma. xrcc7 gene encodes a protein that functions in non-homologous end joining dna repair pathway. non-synony...

Background: The aim of this study was to understand any association between differentiated thyroid carcinoma (DTC) and Ile3434Thr XRCC7 gene polymorphism (GenBank accession number: rs7830743). DTC is the most prevalent thyroid neoplasm, which includes papillary and follicular cell carcinoma. XRCC7 gene encodes a protein that functions in non-homologous end joining DNA repair pathway. Non-synony...

BACKGROUND Lymph node metastasis from differentiated thyroid carcinoma may occur outside of the basins at greatest risk of spread, such as the lateral retropharyngeal lymph nodes. The extensive surgery of traditional approaches to the retropharyngeal space are rarely justified in the treatment of metastatic differentiated thyroid cancer. Therefore, a less invasive surgical approach is advantage...

Molecular imaging based personalized therapy has been a fascinating concept for individualized therapeutic strategy, which is able to attain the highest efficacy and reduce adverse effects in certain patients. Theranostics, which integrates diagnostic testing to detect molecular targets for particular therapeutic modalities, is one of the key technologies that contribute to the success of perso...

While accounting for only 1% of solid organ malignancies (9% in women), thyroid carcinoma is the most common malignancy of the endocrine system. Although most patients have a favorable prognosis, over 1,500 people will die from thyroid carcinoma each year. The spectrum of disease types range from papillary thyroid cancer, which is a well-differentiated indolent tumor, to anaplastic carcinoma, a...

Thyroid nodules are a common clinical problem and with the growing use of diagnostic imaging, the number of thyroid nodules identified and undergoing further diagnostic evaluation by fine-needle aspiration biopsy (FNA) is steadily growing. Only 5 % of all thyroid nodules harbour malignancy and thyroid cancer constitutes only 1 % of all epithelial malignancies worldwide and represents 95 % of al...

Children are not “miniature” adults! Most experts around the world recognize differences between adult and pediatric thyroid cancer emphasize need for specific guidelines population. The American Thyroid Association (ATA) first developed separate Guidelines Treatment of Pediatric Nodules Carcinoma (hereafter, ATA Guidelines) in 2015 [1], which has been revised to date. In September 2022, Europe...

ATA (American Thyroid Association) has published “Treatment Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid Cancer (DTC)” in 1996, and the first “ATA Thyroid Nodules and Differentiated Thyroid Cancer Guidelines” in 2006. The first update was published in 2009 while the most recent update was reported in Thyroid (DOI:10.1089/thy.2015.0020) in the beginning of 2016 as the ...