We propose the use of a robust, biopsy needle-based, fiber-optic tool for routine clinical quantification of tumor oxygenation at the time of diagnostic biopsy for breast cancer. The purpose of this study was to show diffuse reflectance spectroscopy as a quantitative tool to measure oxygenation levels in the vascular compartment of breast cancers in vivo via an optical biopsy technique. Thirty-...

-Diffuse Reflectance Fourier Transform Infrared spectroscopy was used to monitor both molecular interactions and concentrations of volatile organic chemicals adsorbed on a commercial montmorillonite. Chemicals tested included propanoic acid, hexanal, heptanal, trimethylamine, dimethylsulfide and dimethyldisulfide. Diffuse Reflectance Fourier Transform Infrared spectroscopy had several advantage...

Hair follicle offers an excellent model for systems biology and regenerative medicine. So far, the stages of hair follicle growth have been evaluated by histological examination. In this work, a noninvasive spectroscopy was proposed by measuring the diffuse reflectance of mouse skin and analyzing the melanin value. Results show that the skin diffuse reflectance was relatively high when hair fol...

Attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy has been employed for characterization of faceted diamonds. ATR spectra of round brilliant cut natural diamonds of approximately 0.1 ct were observed with excellent spectral quality. The mirror-flat spectrum of the table facet enables a good contact to the ATR crystal with a minimal applied pressure. The observed AT...

Diffuse reflectance spectra are used to determine the optical properties of biological samples. In medicine and forensic science, the turbid objects under study often possess large absorption and/or scattering properties. However, data analysis is frequently based on the diffusion approximation to the radiative transfer equation, implying that it is limited to tissues where the reduced scatteri...

Lens based setups have been explored for non-contact diffuse reflectance measurements to reduce the uncertainty due to inconsistent probe-sample pressure in the past years. However, there have been no reports describing the details of Monte Carlo modeling of lens based non-contact setup for depth sensitive diffuse reflectance measurements to the best of our knowledge. In this study, we first pr...

Supramolecular chirality of crystals which display chirality only in the solid state was for the first time measured by diffuse reflectance circular dichroism (DRCD) spectroscopy for sublimable 1 : 1 pyrene (PYR)-p-benzoquinone (Q) complex, and its integrity was proved.

Recent developments in FT—IR sampling techniques such as diffuse reflectance and photoacoustic spectroscopy are known to obtain new and novel information on solid polymers. In particular, depth profiling can be obtained from the surface using a potassium bromide overlayer. Photoacoustic spectroscopy using coupling gases with different polarizability allows one to determine the nature of absorbe...

tm3+, yb3+ and tm3+/yb3+ doped lavo4 nanostructures were synthe-sized for the first time by using the hydrothermal method with the aid of la(ch3co2)3 as  lanthanum source in presence of oleic acid as surfactant. the products were characterized by x-ray diffraction (xrd), scanning electron microscopy (sem), transmission electron microscopy (tem), photoluminescence (pl) spectroscopy and uv–vis di...