نتایج جستجو برای: digital microfluidic biochip
تعداد نتایج: 325478 فیلتر نتایج به سال:
It gives us great pleasure to present two papers selected from the CASES 2009 program. These two papers were selected from around seventy submissions received after a rigorous process of reviewing. The first paper titled “Tabu Search-Based Synthesis of Digital Microfluidic Biochips with Dynamically Reconfigurable Non-Rectangular Devices” by Elena Maftei, Paul Pop and Jan Madsen, is in the relat...
We have analyzed transcriptomic, proteomic and metabolomic profiles of hepatoma cells cultivated inside a microfluidic biochip with or without acetaminophen (APAP). Without APAP, the results show an adaptive cellular response to the microfluidic environment, leading to the induction of anti-oxidative stress and cytoprotective pathways. In presence of APAP, calcium homeostasis perturbation, lipi...
In vitro cell cultures are used as models for drug discovery. The detection of damage biomarkers such adenylate kinase (AK) is often in screening and biology experiments. A microfluidic platform AK was developed with the capability detecting resulting from lysis 10–100 human colorectal adenocarcinoma HCT116 cells. For this assay, captured on surface microbeads integrated into a device optically...
Microfluidic biochips integrate different biochemical analysis functionalities on-chip and offer several advantages over the conventional biochemical laboratories. In this thesis, we focus on the flow-based biochips. The basic building block of such a chip is a valve which can be fabricated at very high densities, e.g., 1 million valves per cm 2. By combining these valves, more complex units su...
The unabated silicon technology scaling makes design and manufacturing increasingly harder in nanometer VLSI. On one hand, major design objectives such as timing, power, and noise are often conflicting with each other in modern designs with multi-million gates, resulting in complex design closure. On the other hand, design closure no longer guarantees historical yield norm, requiring ever-chall...
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