A digital brain phantom was created from available primate autoradiographic (AR) data for use in emission computed tomography studies. The tissue was radio-labelled with a functional analogue of the PET agent [18F]-fluoro-deoxyglucose (FDG). Following sacrifice of the animal, film records from serial 20 m thickness sections were digitized and calibrated to obtain ground truth 2D spatial distrib...

OBJECTIVES The aim of this study was to evaluate the influences of reconstruction and attenuation correction on the differences in the radioactivity distributions in (123)I brain SPECT obtained by the hybrid SPECT/CT device. METHODS We used the 3-dimensional (3D) brain phantom, which imitates the precise structure of gray matter, white matter and bone regions. It was filled with (123)I soluti...

PURPOSE To develop an anthropomorphic phantom to simulate heart, lung, and blood motion. Magnetic resonance imaging (MRI) is sensitive to image distortion and artifacts caused by motion. Imaging phantoms are used to test new sequences, but generally, these phantoms lack physiological motion. For the validation of new MR-based endovascular interventional and other techniques, we developed a dyna...

In this investigation, we imaged a standard breast phantom and compared the contrast detail curves from a prototype full breast digital mammography system with the corresponding curves for a conventional, analog screen-film system. The full breast digital system exhibited superior contrast detail detectability. The results from this study will be used to plan future clinical evaluations compari...

Objective(s): Alternative normalization methods were proposed to solve the biased information of SPM in the study of neurodegenerative disease. The objective of this study was to determine the most suitable count normalization method for SPM analysis of a neurodegenerative disease based on the results of different count normalization methods applied on a prepared digital phantom similar to one ...

Digital Breast Tomosynthesis (DBT) is a technology that creates three dimensional (3D) images of breast tissue. Tomosynthesis mammography detects lesions that are not detectable with other imaging systems. If image reconstruction time is in the order of seconds, we can use Tomosynthesis systems to perform Tomosynthesis-guided Interventional procedures. This research has been designed to study u...

Introduction: This study, evaluate pediatric digital radiography. Due to the high rates of this test and the high sensitivity of children to ionizing radiation in comparison with adults, it is attempted to achieve near optimal conditions by reducing the dose and maintaining the image quality. The object of the study is to change the irradiation parameters such as kV and mA and ...

INTRODUCTION Dynamic image acquisition protocols are increasingly used in emission tomography for drug development and clinical research. As such, there is a need for computational phantoms to accurately describe both the spatial and temporal distribution of radiotracers, also accounting for periodic and non-periodic physiological processes occurring during data acquisition. METHODS A new 5D ...

Digital breast tomosynthesis (DBT) images of a novel anthropomorphic breast phantom (UPenn phantom) acquired on two breast tomosynthesis systems were analyzed in terms of their power spectra (PS). The β and κ power law coefficients were estimated from 2D planar, tomosynthesis projection images and reconstructed planes. These data were compared to the PS characteristics as retrieved from a group...

To evaluate the characteristics of edge-preserving adaptive filters for selectively eliminating noise without affecting resolution in low-dose scanning, we have developed a digital phantom image and evaluated noise statistical values, noise characteristics, and resolution characteristics. The results confirmed that edge-preserving adaptive filters function as smoothing filters in low-contrast r...