Environmental cues transduced by an endocrine network converge on Caenorhabditis elegans nuclear receptor DAF-12 to mediate arrest at dauer diapause or continuous larval development. In adults, DAF-12 selects long-lived or short-lived modes. How these organismal choices are molecularly specified is unknown. Here we show that coregulator DIN-1 and DAF-12 physically and genetically interact to in...

Some major financial markets are currently reporting that 50% or more of all transactions are now executed by automated trading systems (ATS). To understand the impact of ATS proliferation on the global financial markets, academic studies often use standard reference strategies, such as “AA” and “ZIP”, to model the behaviour of real trading systems. Disturbingly, we show that the reference algo...

In this paper we develop a model of computation for the NRL Protocol Analyzer by modifying and extending the model of computation for Burroughs, Abadi, and Needham (BAN) logic developed by Abadi and Tuttle. We use the results to point out the similarities and di erences between the NRL Protocol Analyzer and BAN logic, and discuss the issues this raises with respect to the possible integration o...

Die Normen DIN EN 61508 und DIN EN 62304 beschreiben Sicherheitsanforderungen für die Entwicklung von Software im medizinischen Umfeld. Diese beinhalten u.a. Vorschriften zur Verifikation und Diagnose (Kapitel C5, DIN EN 61508-7 [Di09]), zur Beurteilung der funktionalen Sicherheit (Kapitel C6, DIN EN 61508-7 [Di09]), zur Implementierung und Verifikation von Software-Einheiten (Kapitel 5.5, DIN ...

this article tries to investigate the range and some features of scientific realism from the perspectives advocated by sayyid jamāl ad-din asad ābādi. it applies grounded theory, documentary research method, and some interpretative and exploratory views. sayyid jamāl has tried to reveal the capacity of religious knowledge including modern world, using hermeneutics insight and qurān’s concepts r...

BACKGROUND The General Practice Research Database (GPRD) and Doctor's Independent Network Database (DIN), are large electronic primary care databases compiled in the UK during the 1990s. They provide a valuable resource for epidemiological and health services research. GPRD (based on VAMP) presents notes as a series of discrete episodes, whereas DIN is based on a system (MEDITEL) that used a Pr...

Background: The General Practice Research Database (GPRD) and Doctor's Independent Network Database (DIN), are large electronic primary care databases compiled in the UK during the 1990s. They provide a valuable resource for epidemiological and health services research. GPRD (based on VAMP) presents notes as a series of discrete episodes, whereas DIN is based on a system (MEDITEL) that used a P...

In this study, we evaluated the sink and source of the surface water along the PRE using a mixing model method with salinity as tracer. The observational data showed that the decreasing of dissolved inorganic nitrogen (DIN) did not closely follow the physical mixing lines of freshwater and modified seawater. In the western part, DIN consumption by phytoplankton and bacteria uptake (ΔDIN)varied ...

Cuvinte cheie: alergie, proteine lapte vacă, toleranţa orală Rezumat: Alergia la proteinele din laptele de vacă este definită ca reacţia imunologică, mediată sau nemediată IgE, la proteinele din laptele de vacă. Afectează populaţia pediatrică în primii 2 ani de viaţă, după această vârstă instalându-se toleranţa la proteinele din laptele de vacă. Sistemul imun intestinal este răspunzator de iniţ...

OBJECTIVE The primary objective of the study was to investigate the feasibility, reliability, and validity of the Dutch digits in noise (DIN) test for measuring speech recognition in hearing aid and cochlear implant users and compare results to the standard sentences-in-noise (SIN) test. DESIGN The relation between speech reception thresholds for DIN test and SIN test was analysed to determin...