OBJECTIVE To determine accurately the relative output factors, defined as the ratio of the nominal dose rate for a given collimator to that of the 60-mm collimator. This is particularly important for radiosurgical treatment of functional disorders, such as trigeminal neuralgia, in which a single large radiation dose is delivered to the target with a small collimator, such as the 5-mm collimator...

PURPOSE Our group previously introduced an in vivo proton range verification methodology in which a silicon diode array system is used to correlate the dose rate profile per range modulation wheel cycle of the detector signal to the water-equivalent path length (WEPL) for passively scattered proton beam delivery. The implementation of this system requires a set of calibration data to establish ...

BACKGROUND Intensity modulated radiation therapy (IMRT) dosimetry verification is routinely conducted via integrated or individual field dosimetry using film or a matrix of detectors. Techniques and software systems are commercially available which use individual field dosimetry measurements as input into algorithms that estimate 3D patient dose distributions on CT scan derived target volumes a...

PURPOSE To validate a machine learning approach to Virtual intensity-modulated radiation therapy (IMRT) quality assurance (QA) for accurately predicting gamma passing rates using different measurement approaches at different institutions. METHODS A Virtual IMRT QA framework was previously developed using a machine learning algorithm based on 498 IMRT plans, in which QA measurements were perfo...

PURPOSE Perform a retrospective dosimetry study of total body irradiation (TBI) on leukemia and bone marrow transplant patients. METHODS The in vivo dosimetry data of 129 patients treated with TBI between 2008 and 2011 were retrieved from the database and analyzed. These patients were mostly treated with the regime of a single fraction or 6 fractions with some exceptions of 8-fraction or 2-fr...

The need for fast, accurate and high resolution dosimetric quality assurance in radiation therapy has been outpacing the development of new and improved 2D and 3D dosimetry techniques. This paper summarizes the efforts to create a novel and potentially very fast, 3D dosimetry method based on the observation of scintillation light from an irradiated liquid scintillator volume serving simultaneou...

Introduction: One of the useful standard quality assurance techniques in radiation therapy is monitoring entrance doses in in-vivo dosimetry. An overall tolerance limit of 5% of the absorbed radiation dose has been recommended by the International Commission of Radiological Units. The implementation of an in vivo dosimet...

Dosimetry of blood irradiation using x-ray beams on a medical linear accelerator has been studied to evaluate the accuracy of a diode detector and the delivery achievable. Variations in applied doses for a standard dual field 6 MV x-ray are measured with a commercial diode detector. Results show that the diode detector measured applied in vitro doses to within 5.4% (2 standard deviations (2 SD)...