Clindamycin is an aminoglycoside used in treatment of skin & soft tissue infections caused by both Methicillin resistant Staphylococcus aureus (MRSA) and Methicillin sensitive Staphylococcus aureus (MSSA). Staphylococcus aureus becomes resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but a...

  Background and Objective: Reliable methods of detection of antimicrobial resistance are of paramount importance in the treatment and management of infections caused by coagulase negative staphylococci (CoNS). The objective of the present study was to compare and evaluate the performance of disc diffusion and E test (Epsilometer test) methods for antimicrobial testing of coagulase ne...

Induced clindamycin resistance poses a major problem for the use of this drug to treat staphylococcal infections. An infectious etiology is often implicated in presence CoNS clinical specimens. A total 183 isolates Staphylococci spp. recovered from different specimens were studied. coagulase test was done select negative Staphylococci, and they confirmed by conventional microbiological techniqu...

17 Recent studies have shown that chromogenic cephalosporin tests are inferior to disc zone edge tests in 18 detecting penicillinase in Staphylococcus aureus isolates resulting in a change to CLSI and EUCAST 19 guidelines in 2012. We sought to confirm these findings using Australian isolates and compare the 20 performance of the CLSI and EUCAST methods which use different disc strengths, penici...

17 Recent studies have shown that chromogenic cephalosporin tests are inferior to disc zone edge tests in 18 detecting penicillinase in Staphylococcus aureus isolates resulting in a change to CLSI and EUCAST 19 guidelines in 2012. We sought to confirm these findings using Australian isolates and compare the 20 performance of the CLSI and EUCAST methods which use different disc strengths, penici...

background and objectives: klebsiella pneumoniae , one of the important causes of nosocomial infections, is the most common extended spectrum β-lactamases (esbls) producing organism. esbls are defined as the enzymes capable of hydrolyzing oxyimino-cephalosporins, monobactams and carbapenems. the aims of this study were to identify esbl-producing k. pneumoniae isolates and detect their antibioti...

BACKGROUND AND OBJECTIVES Methicillin-resistant Staphylococcus aureus (MRSA) is a well-known pathogen with a worldwide distribution. Given the increasing rate of MRSA infections, implementing of reliable, accurate and rapid testing for diagnosis of MRSA is necessary. The aim of this study was to compare four diagnostic methods for detection of MRSA isolates. MATERIALS AND METHODS From Decembe...

Emergence of antimicrobial resistance amongst uropathogenic Escherichia coli and Klebsiella pneumoniae has become a major public health concern of the 21st century [1]. According to World Health Organization (WHO) report 2014, alarming rates of resistance have been reported in all WHO regions due to resistant pathogens like E. coli, K. pneumoniae and Staphylococcus saprophyticus causing urinary...