European Journal of Pharmaceutical Sciences 13 2001 123133 www.elsevier.nllocateejps. Modeling and comparison of dissolution profiles.To compare dissolution profiles between two drug products model dependent curve fitting, statistic analysis and model independent methods can be used. To compare dissolution profiles between two drug products model dependent curve fitting, statistic analysis and ...

Abstract P2-type layered oxides with the general Na-deficient composition Na x TMO 2 ( < 1, TM: transition metal) are a promising class of cathode materials for sodium-ion batteries. The open + transport pathways present in structure lead to low diffusion barriers and enable high charge/discharge rates. However, phase from P2 O2 occurring above 4.2 V metal dissolution at potentials upon disc...

Ye'elimite occurs in nature and calcium sulfoaluminate cements. The thermodynamic properties of synthetic orthorhombic ye'elimite, Ca4Al6O12SO4, were determined experimentally using low-temperature relaxation calorimetry at higher temperatures differential scanning drop calorimetry. heat capacity, Cp, 480 J/mol/K standard entropy, S°, 487 298 K measured. These values compare well with those cal...

In this paper, the two parameter ADK entropy, as a generalized of Re'nyi entropy, is considered and some properties of it, are investigated. We will see that the ADK entropy for continuous random variables is invariant under a location and is not invariant under a scale transformation of the random variable. Furthermore, the joint ADK entropy, conditional ADK entropy, and chain rule of this ent...

Clarithromycin (CLA), a broad-spectrum macrolide, is a poorly soluble drug with dissolution rate limited absorption. The aim of this investigation was to prepare CLA nanoparticles from a ternary ground mixture in the presence of sodium lauryl sulfate (SLS) and polyvinyl pyrrolidone (PVP) as co-grinding water-soluble compounds, in order to improve the drug dissolution rate. Different weight rati...

The purpose of this study is to define the concepts of Tsallis entropy and conditional Tsallis entropy of fuzzy partitions and to obtain some results concerning this kind entropy. We show that the Tsallis entropy of fuzzy partitions has the subadditivity and concavity properties. We study this information measure under the refinement and zero mode subset relations. We check the chain rules for ...

A high density of local natural and human-induced ground deformation 11 structures resulting from the presence of evaporites occur extensively 12 around Zaragoza (NE Spain), posing risks to infrastructures, buildings and 13 agriculture. We studied the potential of a series of interferograms 14 constructed from 29 ERS -1/2 images to detect different types of ground 15 deformation related to evap...

Abstract Up to now, we know only a little about the causal effect of international migration on partnership stability, with few existing analyses being restricted internal or from less developed countries Global North. Using longitudinal data German citizens [the Emigration and Remigration Panel Study plus Family (pairfam)], this study contributes literature primarily in two ways: first, by com...

Drug product performance testing is an important part of quality-by-design approaches, but this process often lacks the underlying mechanistic understanding of the complex interactions between the disintegration and dissolution processes involved. Whereas a recent draft guideline by the US Food and Drug Administration (FDA) has allowed the replacement of dissolution testing with disintegration ...