Increased pulmonary vascular resistance in preterm newborn infants with respiratory distress syndrome is suggested, and endothelin-1 plays an important role in pulmonary vascular reactivity in newborns. We determined umbilical cord blood and neonatal (second sample) levels of endothelin-1 in 18 preterm newborns with respiratory distress syndrome who had no clinical or echocardiographic diagnosi...

PURPOSE OF REVIEW Acute respiratory distress syndrome has been considered a morphologic and functional expression of lung injury caused by a variety of insults. Two distinct forms of acute respiratory distress syndrome/acute lung injury are described, because there are differences between pulmonary acute respiratory distress syndrome (direct effects on lung cells) and extrapulmonary acute respi...

Acute respiratory distress syndrome is characterized by a diffuse inflammatory reaction of lung parenchyma induced by a direct insult to the alveolar epithelium (pulmonary acute respiratory distress syndrome) or an indirect lesion through the vascular endothelium (extrapulmonary acute respiratory distress syndrome). The main therapeutic strategy for acute respiratory distress syndrome is the ve...

Lung protection strategy as an effective treatment in acute respiratory distress syndrome

Acute respiratory distress syndrome is a challenging entity for the intensivist. The pathological hallmark of the acute phase is diffuse alveolar damage, which is present in approximately half of living patients with acute respiratory distress syndrome. It is clear that respiratory support for acute respiratory distress syndrome has gradually been improving over recent decades. However, it is a...

High survival rate in 122 ARDS patients managed according to a clinical algorithm including extracorporeal membrane oxygenation. beneficial effects of the 'Open Lung Approach' with low distending pressures in acute respiratory distress syndrome. Effect of protective-ventilation strategy on mortality in the acute respiratory distress syndrome. 6 The Acute Respiratory Distress Syndrome Network. V...

Background: Chest radiography is one of the most usual diagnostic tools for respiratory distress. Objective: The purpose of this study is to assess the specificity, sensitivity and clinical value of chest radiography of neonates with respiratory distress.Patients and Methods: A descriptive- analytical study was conducted on 102 neonates that were in neonatal intensive care unit of Imam Reza and...

Neonatal respiratory distress syndrome [4], previously called hyaline membrane disease, is a respiratory disease affecting premature newborns. Neonatal respiratory distress syndrome [4] involves shallow breathing, pauses between breaths that last a few seconds, or apnea, and a bluish tinge to the infant?s skin. The syndrome occurs when microscopic sacs called alveoli in infant lungs do not prod...

Neonatal respiratory distress syndrome [4], previously called hyaline membrane disease, is a respiratory disease affecting premature newborns. Neonatal respiratory distress syndrome [4] involves shallow breathing, pauses between breaths that last a few seconds, or apnea, and a bluish tinge to the infant?s skin. The syndrome occurs when microscopic sacs called alveoli in infant lungs do not prod...

Neonatal respiratory distress syndrome [4], previously called hyaline membrane disease, is a respiratory disease affecting premature newborns. Neonatal respiratory distress syndrome [4] involves shallow breathing, pauses between breaths that last a few seconds, or apnea, and a bluish tinge to the infant?s skin. The syndrome occurs when microscopic sacs called alveoli in infant lungs do not prod...