general kind of encroachment of river is constructing a bridge on it. purpose of encroachment of river is occupation part of river and flood plain for constructing bridge. often being economical of bridge innovation affirmated that most of encroachment take place to river and flood plain, which this encroachment can be in form of embankment in flood plain of river or into the main bed of river ...

We present stochastic barcoding (SB), a method for tracking cell identity across analytical platforms. SB uses a randomly generated code based on number, color and position of beads encapsulated together with a set of cells of interest. We demonstrate SB use in an application where cells are transferred from a microwell array into a microtitre plate while keeping their identity, and obtain an a...

Mechanistic models of charge transfer (CT) in macromolecules often focus on CT energetics and distance as the chief parameters governing CT rates and efficiencies. However, in DNA, features unique to the DNA molecule, in particular, the structure and dynamics of the DNA base stack, also have a dramatic impact on CT. Here we probe the influence of subtle structural variations on base-base CT wit...

Recently, we demonstrated chromosome instability (CIN) in human cleavage stage embryogenesis following in vitro fertilization (IVF). CIN not necessarily undermines normal human development (i.e. when remaining normal diploid blastomeres develop the embryo proper), however it can spark a spectrum of conditions, including loss of conception, genetic disease and genetic variation development. To s...

The role of base motions in delocalization and propagation of charge through double helical DNA must be established experimentally and incorporated into mechanistic descriptions of DNA-mediated charge transport (CT). Here, we address these fundamental issues by examining the temperature dependence of the yield of CT between photoexcited 2-aminopurine (Ap) and G through DNA bridges of varied len...

this paper presents a new bridge management system (j-bms). it is integrated with a concrete bridge rating expert system that can be used to evaluate the serviceability of existing concrete bridges. the proposed j-bms not only evaluates the performance of bridges, but also offers a rehabilitation strategy based on a combination of maintenance cost minimization and quality maximization. in this ...

We developed several novel tools to genome wide screen for CNVs and SNPs in single cells. When applied to cleavage stage embryos from young fertile couples we discovered, unexpectedly, an extremely high incidence of chromosomal instability, a hallmark of tumorigenesis (Vanneste et al., Nature Medicine, 2009; Vanneste et al., Hum.Reprod., 2011). Not only mosaicisms for whole chromosome aneuploid...