Donor organ shortage continues to limit the availability of liver transplantation, a successful and established therapy of end-stage liver diseases. Strategies to mitigate graft shortage include the utilization of marginal livers and recently ex-situ normothermic machine perfusion devices. A 59-year-old woman with cirrhosis due to primary sclerosing cholangitis was offered an ex-situ machine pe...

PurposeThe increased use of donors after circulatory death (DCD) has expanded the breath organ donation across many heart transplant centers. However, there are concerns about stability and quality compared to traditional brain (DBD) organs. The objective our study is analyze differences between DCD DBD.MethodsSingle center, retrospective data from procured inception program at institution. We ...

When hard tissue augmentation is scheduled as a part of an oral rehabilitation, prior to the treatment, it is important to assess if the quality of the underlying gingiva at the recipient site can support the bone grafting procedure. The most frequent complication during autologous onlay grafts are wound dehiscences in the recipient site, so the integrity of soft tissues is a basic aspect of su...

In our current era where shortage of liver grafts is commonplace, utilization of traumatic liver grafts may represent an opportunity to expand the organ donor pool without compromising graft survival. However, data on liver transplantation using a fractured liver allograft is scarce, with only small case series and reports found in the literature. In this report, we describe our experience with...

OBJECTIVES To compare transplant outcomes between expanded criteria donor kidneys and standard criteria donor kidneys. MATERIALS AND METHODS All adult renal transplants from deceased donors performed in Saudi Arabia over a 24-month period were included. Donor and recipient factors were recorded, and their effects on outcomes with expanded criteria donor and standard criteria donor kidneys wer...

The results of 219 orthotopic human liver transplants performed during 1985 at the University of Pittsburgh were reviewed to determine whether donor parameters could be used to predict the quality of early graft function. Multivariate discriminant analysis demonstrated that traditional parameters of donor assessment are unreliable predictors of poor graft function. Furthermore, 56% of the donor...

BACKGROUND Renal transplant recipients of older deceased-donor kidneys have reduced allograft survival. However, the impact of donor-recipient age difference on live-donor kidney transplant outcomes, where donors are older than recipients, remains unclear. METHODS Using the Australia and New Zealand Dialysis and Transplant Registry, all primary live-donor kidney transplant recipients in Austr...

BACKGROUND Debate continues about what split-thickness skin graft donor-site dressing provides the best outcomes for patients at the lowest cost. The goal of this systematic review was to determine which donor-site dressings are associated with the best outcomes for the following: pain, infection rate, healing quality, healing rate, quality of life, and cost. METHODS A comprehensive literatur...

Primary graft dysfunction is an important cause of morbidity and mortality after cardiac transplantation. Donor brain stem death (BSD) a significant contributor to donor heart primary dysfunction. There remain substantial gaps in the mechanistic understanding peritransplant One these metabolism metabolic function. The healthy “omnivore,” capable utilizing multiple sources nutrients fuel its eno...

Orthotopic liver transplantation (OLT) has become the effective treatment for end-stage liver diseases. Since the 1980s, the successful rate of liver transplantation has increased with the improvement of operative methods and the use of University of Wisconsin (UW) solution. Nevertheless, liver procurement and implantation are inevitably associated with allograft damage. Lack of donor liver hin...