M. sylvestris inhibits C. albicans biofilm formation Journal of Herbmed Pharmacology, Volume 6, Number 2, April 2017 http://www.herbmedpharmacol.com 63 increased expression of drug efflux pump genes and metabolic plasticity provide protection by preventing the penetration of host immune factors and antifungals agents into the extracellular matrix in comparison to planktonic cells (3,6-10). The ...

Background: Dorema aucheri (Apiaceae) grows in west and southwest of Iran. Young leaves of this plant are used orally as pickle or for cooking some local foods, as well as for the treatment of parasitic digestive infections and constipation. Objective: The aim of present study was evaluation of cytotoxic potential and total phenols determination of D. aucheri young aerial parts extract and fr...

In the present study, changes of total phenolic concentration and radical-scavenging activity were evaluated in the shoots of Artemisia aucheri -a medicinal plantthat had been exposed as seeds to magnetic fields (90 or 200 mT for 5 and 20 min) and that were irrigated for one month with NaCl (150 mM) under glasshouse conditions. Total phenolic content and radical-scavenging activity decreased in...

Allergic rhinitis or hay fever, is the most frequently occuring airway disease of our time. Therefore, the aim of this study was to evaluate of the allergenicity effect of Artemisia aucheri extract. In this research, flowrs of Artemisia aucheri were collected from Isfahan around, Iran in September 2012. Flowes were extracted using phosphate-buffered saline, PH 7.4. Three concentration of extrac...

PURPOSE In the present study cytotoxic effects of the alcoholic extract of Dorema Glabrum seed on viability of WEHI-164 cells, mouse Fibrosarcoma cell line and L929 normal cells were compared with the cytotoxic effects of Taxol (anticancer and apoptosis inducer drug). METHODS To find out the plant extract cytotoxic effects, MTT test and DNA fragmentation assay, the biochemical hallmark of apo...

We aimed to investigate the apoptotic effects of the methanolic extract of Dorema glabrum seed on WEHI-164, cancerous cells in comparison with L929, normal cells and compared them with the cytotoxic effects of Taxol. So, MTT test and DNA fragmentation assay were performed on cultured and treated cells. Also electrophoresis which was followed by immunoblotting was done to survey the production o...

Ten extracts with different polarity from two Iranian Artemisia species, A. armeniaca Lam. and A. aucheri Boiss, were screened for their antimalarial properties by in vitro   β -hematin formation assay. Dichloromethane (DCM) extracts of both plants showed significant antimalarial activities with IC50 values of 1.36±0.01 and 1.83±0.03 mg/mL and IC90 values of 2.12±0.04 and 2.62±0.09 mg/mL for A....