Purpose This study is intended to compare dose-volume parameters evaluated using different forward planning- optimization techniques, involving two applicator systems in intracavitary brachytherapy for cervical cancer. It looks for the best applicator-optimization combination to fulfill recommended dose-volume objectives in different high-dose-rate (HDR) fractionation schedules. Material and ...

BACKGROUND AND PURPOSE Prospective assessment of dysphagia and trismus in chemo-IMRT head and neck cancer patients in relation to dose-parameters of structures involved in swallowing and mastication. MATERIAL AND METHODS Assessment of 55 patients before, 10-weeks (N=49) and 1-year post-treatment (N=37). Calculation of dose-volume parameters for swallowing (inferior (IC), middle (MC), and supe...

The antitumor activity of ethanol extract of Prosopis glandulosa Torr. (EPG) was evaluated against Ehrlich ascites carcinoma (EAC) tumor model in Swiss albino mice on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. Oral administration of EPG at the dose of 100, 200 and 400 mg/Kg, significantl...

The antitumor activity of ethanol extract of Prosopis glandulosa Torr. (EPG) was evaluated against Ehrlich ascites carcinoma (EAC) tumor model in Swiss albino mice on dose dependent manner. The activity was assessed using survival time, average increase in body weight, hematological parameters and solid tumor volume. Oral administration of EPG at the dose of 100, 200 and 400 mg/Kg, significantl...

PURPOSE We evaluated patient and treatment parameters correlated with development of temporal lobe radiation necrosis. METHODS AND MATERIALS This was a retrospective analysis of a cohort of 66 patients treated for skull base chordoma, chondrosarcoma, adenoid cystic carcinoma, or sinonasal malignancies between 2005 and 2012, who had at least 6 months of clinical and radiographic follow-up. The...

The purpose of this study was to estimate locally accumulated dose to the bladder in multi-fraction high-dose-date (HDR) image-guided intracavitary brachytherapy (IG-ICBT) for cervical cancer, and study the locally-accumulated dose parameters as predictors of late urinary toxicity. A retrospective study of 60 cervical cancer patients who received five HDR IG-ICBT sessions was performed. The bla...

introduction: this study was designed to evaluate dosimetric parameters such as rectal dose, bladder dose, integral dose (id), homogeneity index (hi) and conformity index (ci) in various treatment plans for prostate cancer. materials and methods: pelvic computed tomography (ct) scans of 27 patients were acquired and transferred to the rtdoseplan treatment planning system. for each patient, 8 co...

background: busulfan (bus) is a chemotherapy drug that is widely used for cancer treatment. however, administration of busulfan may cause temporary or permanent sterility in male patients. therefore, reduction of this side is necessary. objective: evaluation of the protective effects of l-carnitine and testis homogenized tissue (tht) on sperm parameters and the testis structure after busulfan t...