نتایج جستجو برای: double dose vaccination
تعداد نتایج: 591550 فیلتر نتایج به سال:
We report here a large scale, double blind immunoprophylactic trial of a leprosy vaccine based on Mycobacterium w (Mw) in an endemic area of Kanpur Dehat, Uttar Pradesh, India. A population of 420,823 spread over 272 villages was screened where 1226 multibacillary (MB) and 3757 paucibacillary (PB) cases of leprosy were detected. A total of 29,420 household contacts (HHC) of these patients were ...
Hepatitis B virus (HBV) chronic infection represents a significant cause of morbidity and mortality worldwide. While traditional intramuscular (IM) HBV vaccination is an excellent method for robust and sustained seroconversion in healthy individuals, its efficacy in chronic liver disease is sub-optimal and scant data exists in the post-liver transplant state. Importantly, HBV complications are ...
We report the safety and immunogenicity of a double lysine and pantothenate auxotroph of Mycobacterium tuberculosis in mice. The DeltalysA DeltapanCD mutant is completely attenuated in immunocompromised SCID and gamma interferon knockout mice yet induces short-term and long-term protection in immunocompetent and CD4-deficient mice following single-dose subcutaneous vaccination.
conclusions single dose therapy of mtx has sufficient power and efficacy in the treatment of ectopic pregnancy, however in patients with higher serum level of β-hcg, the successful treatment increases by using double dose method. using double dose also could decrease the necessity of operation, re-administration of mtx, and duration of hospitalization. results results showed that the rate of su...
We report the findings of three randomized, double-blind, placebo-controlled Phase I studies undertaken to support licensure of the liquid formulation of the human G1P[8] rotavirus (RV) vaccine (RIX4414; GlaxoSmithKline Biologicals SA) in China. Healthy adults aged 18-45 y (n=48) and children aged 2-6 y (n=50) received a single dose of the human RV vaccine or placebo. Healthy infants (n=50) age...
BACKGROUND Apical Membrane Antigen 1 (AMA1) of Plasmodium falciparum merozoites is a leading blood-stage malaria vaccine candidate. Protection of Aotus monkeys after vaccination with AMA1 correlates with antibody responses. STUDY DESIGN/RESULTS A randomized, controlled, double-blind phase 1 clinical trial was conducted in 54 healthy Malian adults living in an area of intense seasonal malaria ...
long-term protection against hepatitis b virus (hbv) is dependent on persistence of anti-hbs antibodies and/or strong immunological memory. in this study we evaluated the persistence of anti-hbs antibodies in healthy iranian children 5 years after primary vaccination and the response to a booster dose using recombinant hepatitis b vaccine. totally, 81 children who had received primary course of...
background: immunization against diphtheria, tetanus and pertussis (dtp) has long been applied in iran using whole cell vaccine. despite the role of whole cell dtp (dtwp) vaccine in reduction of mortality as a result of disastrous diseases such as diphtheria, tetanus, and pertussis, serious local and systemic complications have been attributed to these vaccines. this study was performed to det...
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