We develop a new strategy to prepare quantum dot (QD) barcode particles by polymerizing double-emulsion droplets prepared in capillary microfluidic devices. The resultant barcode particles are composed of stable QD-tagged core particles surrounded by hydrogel shells. These particles exhibit uniform spectral characteristics and excellent coding capability, as confirmed by photoluminescence analy...

This paper reports the design and construction of a plastic-glass hybrid microfluidic platform for performing protein crystallization trials in nanoliter double emulsions. The double emulsion-based protein crystallization trials were implemented with both the vapor-diffusion method and microbatch method by controlling the diffusion of water between the inner and outer phases and by eliminating ...

We present a novel approach for fabricating monodisperse phospholipid vesicles with high encapsulation efficiency using controlled double emulsions as templates. Glass-capillary microfluidics is used to generate monodisperse double emulsion templates. We show that the high uniformity in size and shape of the templates are maintained in the final phospholipid vesicles after a solvent removal ste...

Double emulsions are useful templates for microcapsules and complex particles, but no method yet exists for making double emulsions with both high uniformity and high throughput. We present a parallel numbering-up design for microfluidic double emulsion devices, which combines the excellent control of microfluidics with throughput suitable for mass production. We demonstrate the design with dev...

The evolution of double-emulsion droplets is of great importance for the application of microdroplets and microparticles. We study the driving force of the dewetting process, the equilibrium configuration and the dewetting time of double-emulsion droplets. Through energy analysis, we find that the equilibrium configuration of a partial engulfed droplet depends on a dimensionless interfacial ten...

Double emulsions are a promising formulation for encapsulation and targeted release in pharmaceutics, cosmetics food. An inner water phase is dispersed an oil phase, which again emulsified second phase. The encapsulated can be released via diffusion or coalescence, neither of desired during storage but might intended application. two interfaces double emulsion stabilized by hydrophilic lipophil...

Double layer encapsulation of Lactobacillus acidophilus by Emulsion and spray-drying Techniques: Study characteristics survival microcapsules under simulated gastrointestinal conditions

This double-blind, randomized, placebo-controlled trial evaluated the effectiveness of fennel seed oil emulsion in infantile colic. The results showed that the colic of 65% of the infants in the treatment group was eliminated compared with 23.7% in the control group; this difference was considered statistically significant. The study indicates that fennel seed oil emulsion is superior to placeb...

Curcumin and catechin are naturally occurring phytochemicals with extreme sensitivity to oxidation and low bioavailability. We fabricated a water-in-oil-in-water (W/O/W) double emulsion encapsulating hydrophilic catechin and hydrophobic curcumin simultaneously. The co-loaded emulsion was fabricated using a two-step emulsification method, and its physicochemical properties were characterised. Vo...