Dicer is a specialized nuclease that produces RNA molecules of specific lengths for use in gene silencing pathways. Dicer relies on the correct measurement of RNA target duplexes to generate products of specific lengths. It is thought that Dicer uses its multidomain architecture to calibrate RNA product length. However, this measurement model is derived from structural information from a protoz...

The dynamic behaviour of compressed CH3F and CF3H has been studied between 150 and 400 K and to pressures of 200 MPa by measuring the spin-lattice relaxation times (T1) of the proton and fluor nuclei. Also the deuteron T 1 of CD3F and CF3D were obtained in the whole p, T range. Both substances reveal a significant non-Arrhenian behaviour when the whole temperature range is studied. In addition ...

In an age of “Big Data” the study history and archaeology religion faces exponentially increasing quantity range data scholarly interpretation. For student scholar alike, new tools that allow for efficient accurate inquiry are a necessity. Here, open-access digital Database Religious History (DRH) is presented as one such tool addresses this need well suited use in classroom. article, we presen...

BACKGROUND Dexmedetomidine is a highly selective α2 adrenergic agonist that has been shown to decrease the intensity of opioid-induced hyperalgesia (OIH). We aimed to investigate the antihyperalgesic effects of dexmedetomidine on high-dose remifentanil-induced hyperalgesia. METHODS Ninety American Society of Anesthesiologists physical status I-II patients undergoing laparoscopically assisted ...

Abstract The sustainable, passive climatisation of display cases using saturated salt solutions is rarely applied nowadays. These adjust the atmospheric humidity to specific deliquescence relative (DRH) salt. Practical problems like risk spilling or ‘creeping’ salts can be overcome. DRH suitable does not depend significantly on temperature. Solutions were Oddy-tested check for corrosive emissio...

With funding from the Center for Disease Control and Prevention’s Division of Reproductive Health (DRH) and the Health Resources and Services Administration’s Maternal and Child Health Bureau (MCHB), the Association of Maternal and Child Health Programs (AMCHP) and CityMatCH have formed a Women’s Health Partnership to build state and local capacity to promote safe motherhood and enhance women’s...