First, consider possible causes of the inadequate response to an antidepressant, then weigh treatment options in light of the characteristics of the individual patient and therapy. When managing a patient with nonpsychotic depression and inadequate response to the maximum dose of a single antidepressant, the physician should first identify factors that may contribute to the poor response, such ...

Selective serotonin reuptake inhibitors (SSRIs) are the drug of choice for treatment of patients with panic disorder. Most patients have a favorable response to SSRI therapy; however, 30 percent will not be able to tolerate these drugs or will have an unfavorable or incomplete response. Strategies to improve management of such patients include optimizing SSRI dosing (starting at a low dose and ...

the aim of this study was to compare the lateral window and osteotome techniques for sinus lifting using histological and histomorphometric methods.in this clinical trial 10 patients (a total number of 14 sinus areas) who needed implant treatment in the atrophic posterior maxilla were enrolled. in all the cases the residual bone height between the sinus floor and the alveolar crest was less tha...

Antidepressant augmentation strategies are commonly employed to treat depressed patients who do not respond to antidepressant monotherapy. Neuroinflammatory mechanisms have been implicated in depression, and nonsteroidal anti-inflammatory drugs (NSAIDs) have been found effective in animal models of depression both in monotherapy and when used to augment antidepressant drugs. However, results wi...

introduction in spite of multiple applications of bioactive glasses, these materials have not been evaluated yet for ridge augmentation. due to the large number of patients who need ridge augmentation and the benefits of nova bone, in comparison with other alloplasts, this study was fulfilled for evaluation of nova bone ability in ridge augmentation. methods the samples of this experimental stu...

R. Eric Phelts, Ph.D., is a research engineer in the Department of Aeronautics and Astronautics at Stanford University. He received his B.S. in Mechanical Engineering from Georgia Institute of Technology in 1995, and his M.S. and Ph.D. in Mechanical Engineering from Stanford University in 1997 and 2001, respectively. His research involves signal deformation monitoring techniques and analysis fo...

objective: alveolar ridge preservation in patients with inadequate bone volume is one treatment option for successful implant placement and can be done by using bone graft materials. on the other hand, ceno bone has been recently produced by hamanand saz baft kish co. as a bone bioimplant of allograft origin. this study aimed to assess the clinical, histologic and histomorphometric results of b...

capsular contraction is a frequent complication following breast augmentation. on the other hand, capsular weakness, a not widely recognized complication, may occur around the implant. a weak capsule allows the migration of the prosthesis to the lateral region of the thoracic region or inferiorly, towards the abdomen, due to gravitational forces. the cause of capsular weakness remains unresolve...

objective: to manage a treatment resistant depression, clinicians may add a second medicationto the first antidepressant drug. the aim of the current research was to study the outcome of augmentation of citalopram with nortryptiline or triiodothyronine in a randomized clinical trial. methods: we selected 48 adult outpatients with a diagnosis of non-psychoticmajor depressive disorder who had not...

BACKGROUND MemoryShape (Contour Profile Gel) is a textured contoured implant filled with a cohesive silicone gel intended for use in aesthetic and reconstructive breast surgery. The 6-year summary of the clinical outcomes and satisfaction rates for this device from a 10-year, prospective, open-label, multicenter clinical trial is presented. METHODS According to 2006 guidelines set forth by th...