BACKGROUND Previous studies have identified medication errors in preparing and administering intravenous medicines of 13-84% in hospitals in individual countries. OBJECTIVE To compare the effect of the design and implementation of systems for the preparation and administration of intravenous therapy in hospitals in three European countries on the number of observed medication errors. To gain ...

In the present investigation an attempt has been made to explore traditional medicinal knowledge of plant species used against rheumatism by the Bhoxa tribe of district Dehradun. An ethnobotanical survey was carried out among the tribal people in all seasons to collect the relevant information about the medicinal uses of wild plants. Frequent field trips were made for the collection of plant sp...

IMPORTANCE Bevacizumab acquired from compounding pharmacies for intravitreal injection may cause infectious and noninfectious inflammation. In addition to safety issues, the drug itself may have variable efficacy associated with product aliquoting, handling, and distribution. OBJECTIVE To conduct surveillance cultures, evaluate endotoxin levels, and assess protein concentrations of bevacizuma...

Medications given via the intravenous (IV) route provide rapid drug delivery to the body. IV therapy is a complex process requiring proper drug preparation before administration to the patients. Therefore, errors occurring at any stage can cause harmful clinical outcomes to the patients, which may lead to morbidity and mortality. This was a prospective observational study with the objectives to...

Corresponding author Sabrina de Souza Campus Universitário Reitor João David Ferreira Lima, Florianópolis, SC, Brazil. Zip Code: 88040-900 [email protected] Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil. Escola Paulista de Enfermagem, Universidade Federal de São Paulo, São Paulo, SP, Brazil. Conflicts of interest: none to report. Abstract Objective: To understand the ...

The formulation scientist’s key goal is to achieve long-term stability of a drug compound. In the case of protein drugs, stabilization means not only maintaining the native chemical structure, but the native secondary and higher order structures necessary for biological activity (Cleland et al., 1993; Manning et al., 1989). Denaturation, as it is defined in this context, will be any non-native ...

SURADARU LEPA CHURNA'-A Compound drug formulation in Ayurvedic system of medicine was analysed. The proximate chemical analysis, the microscopic method of identifying their ingredients, flourescese study and thin layer chromatographic studies of the drug have been reported in this paper.

'HAB-E-BUKHAR' - a compound drug formulation in Unani System of medicine has been analysed. The microscopic method of identification of few of its ingredients (Sath-e-gulu, Thabasheer); Quantitative analysis of Quinine sulphate, other physio-chemical contents and the T.L.C. of the drug have also been reported here.

The purpose of this study was to investigate the quality of hydroxyprogesterone caproate (HPC) active pharmaceutical ingredient (API) sources that may be used by compounding pharmacies, compared to the FDA-approved source of the API; and to investigate the quality of HPC injection samples obtained from compounding pharmacies in the US, compared to the FDA-approved product (Makena(®)). Samples o...

David W. Newton, BS, PhD, FAPhA Bernard J. Dunn School of Pharmacy Shenandoah University Winchester, Virginia Lawrence A. Trissel, BS, RPh, FASHP M.D. Anderson Cancer Center The University of Texas Houston, Texas Editor’s Note In January 2004, Chapter <797> in the United States Pharmacopeia 27 became the first practice standards for sterile pharmacy compounding in US history that may be enforce...