Sofosbuvir is an antiviral drug that entirely revolutionized the treatment of hepatitis C. This drug has an Iranian commercial brand, which is known as Ledibiox. Several adverse events have been reported with this drug, including syncope, pancolitis, and exacerbated pulmonary arterial hypertension; however, arrhythmia rarely has been described through the literature. Here, we report a 40-year-o...

a bstract background: medication errors and adverse drug events of high alert medication are one of the major problems in therapeutic system. the purpose of the present study was to investigate ‎the effect of clinical supervision model on high alert medication safety in intensive care units nurses. materials and methods: this was a quasi-experimental study conducted on 32 nurses of intensive ca...

Background: Polypharmacy is the use of five or more types drugs in a therapy simultaneously. The polypharmacy increases potential for drug-drug interactions. In COVID-19 therapy, varied antiviral and non-antiviral medications allow increased drug Objective: To determine relationship between interactions therapy. Method: This an analytical observational study with retrospective data retrieval us...