This study examined the impact of 4 weeks of either complete cessation of training (DTR) or a tapering period (TAP; short-term reduction of the strength training volume, while the intensity is kept high), subsequent to 16 weeks of periodized heavy resistance training (PRT) on strength/power gains and the underlying physiologic changes in basal circulating anabolic/catabolic hormones in strength...

The object of this study was to examine changes in muscular strength, power, and resting hormonal concentrations during 6 weeks of detraining (DTR) in recreationally strength-trained men. Each subject was randomly assigned to either a DTR (n = 9) or resistance training (RT; n = 7) group after being matched for strength, body size, and training experience. Muscular strength and power testing, an...

It is known that some dimeric tandem repeats (DTR) are very abundant in noncoding DNA. We nd that certain DTR length distribution functions in noncoding DNA can be t by a power law function. We analyze a simpli ed model of unequal chromosomal crossing over and nd that it produces a stable power law length distribution function, with the exponent = 2. Although the exponent predicted by this mode...

BACKGROUND Pseudonormal Doppler E-wave filling patterns indicate diastolic dysfunction but are indistinguishable from the normal filling pattern. For accurate classification, maneuvers to alter load or to additionally measure peak E' are required. E-wave deceleration time (DT) has been fractionated into its stiffness (DTs) and relaxation (DTr) components (DT=DTs+DTr) by analyzing E-waves via th...

BACKGROUND AND AIMS Increased evidence suggests a pro-atherogenic role for conventional dendritic cells (cDC). However, due to the lack of an exclusive marker for cDC, their exact contribution to atherosclerosis remains elusive. Recently, a unique transcription factor was described for cDC, namely Zbtb46, enabling us to selectively target this cell type in mice. METHODS Low-density lipoprotei...

We have investigated whether the nonpathogenic gram-positive bacteria Staphylococcus xylosus and S. carnosus can display a whole domain of a toxic protein on their surface and if such vectors are suitable for immunization of BALB/c mice. The nucleotide sequence encoding the receptor-binding domain (DTR; amino acids 382 to 535) of diphtheria toxin (DT) was inserted into plasmids pSE'mp18ABPXM an...

Observations show that the surface diurnal temperature range (DTR) has decreased since 1950s over most global land areas due to a smaller warming in maximum temperatures (Tmax) than in minimum temperatures (Tmin). This paper analyzes the trends and variability in Tmax, Tmin, and DTR over land in observations and 48 simulations from 12 global coupled atmosphere-ocean general circulation models f...

It has been widely accepted that diurnal temperature range (DTR) decreased on a global scale during the second half of the twentieth century. Here we show however, that the long-term trend of annual DTR has reversed from a decrease to an increase during the 1970s in Western Eu-rope and during the 1980s in Eastern Europe. The analysis is based on the high-quality dataset of the European Climate ...

BACKGROUND Although the seasonal variation and the effect of cold temperature on heart failure (HF) morbidity have been well documented, it is unknown whether the temperature variation within a day, that is, diurnal temperature range (DTR), is an independent risk factor for HF. We hypothesized that large DTR might be a source of additional environmental stress and, therefore, a risk factor for ...