Between May 2003 and July 2006, we carried out percutaneous patent ductus arteriosus closure using a Nit-Occlud device in 28 patients, who had a median age of 1.8 years (range 0.5-21 years) and a median weight of 10.9 kg (range 5.9-64 kg). The ductus arteriosus had several different morphologic forms, and there was one postsurgical recanalization of the ductus arteriosus. The median minimum duc...

A seven-week-old infant with aortic origin of the right pulmonary artery and patent ductus arteriosus is reported. During preoperative studies, a balloon catheter was used to occlude the ductus arteriosus in order to define the status of the pulmonary vascular bed. Corrective operation was performed by anastomosis of the anomalous right pulmonary artery to the main pulmonary trunk and ligation ...

The rare anomaly of a right aortic arch, distal origin of the left subclavian artery, and posterior left ductus arteriosus (forming a vascular ring) plus a right ductus arteriosus is described in an infant with d-transposition of the great arteries with an intact septum. The presence of a right aortic arch and distal left subclavian artery with bilateral ductus arteriosus has not been described...

The increased survival of small neonates with hyaline membrane disease has led to an increase in patent ductus arteriosus in such neonates. Durirng the period of this study patent ductus arteriosus occurred in 21 % of all newborn infants who weighed <2500 g, and were seen at this hospital; the proportion increased with decreasing birthweight and gestational age.1 Patent ductus arteriosus often ...

Clinical studies of a family of Saluki dogs demonstrated a spectrum of cardiac malformations, which ranged from mild thickening of a pulmonic valve leaflet to a complex condition composed of tricuspid valve insufficiency, pulmonic stenosis, patent ductus arteriosus, and mitral valve insufficiency. All affected dogs had patent ductus arteriosus or ductus diverticulum, which is an incomplete or a...

Contractile responses of rings of ductus arteriosus from fetal and neonatal guinea pigs were studied in buffered Krebs-Henseleit solutions of various oxygen tensions. Oxygen-induced contraction of ductus arteriosus increased with gestational age, peaking at term and attenuating within 24 h after birth. Contractions of ductus in response to potassium were not different in term and preterm fetuse...

The effects of patent ductus arteriosus upon the circulation were studied by Eppinger, Burwell, and Gross (1). Later, Dexter, Haynes, Burwell, Eppinger, Sosman, and Evans (2) described preoperative and postoperative hemodynamic studies obtained by cardiac catheterization in a patient with patent ductus arteriosus. Since the presence of a patent ductus arteriosus can. be detected by physical exa...

The increased survival of small neonates with hyaline membrane disease has led to an increase in patent ductus arteriosus in such neonates. Durirng the period of this study patent ductus arteriosus occurred in 21 % of all newborn infants who weighed <2500 g, and were seen at this hospital; the proportion increased with decreasing birthweight and gestational age.1 Patent ductus arteriosus often ...

Ultrasonic visualization of the ductus arteriosus in first and second trimester pregnancies was compared with postmortem preparations. Twenty human fetal postmortem specimens from 8 to 19 weeks menstrual age were examined, 11 with microscopic reconstruction, nine with macroscopic dissection. The angle between ductus arteriosus and aortic isthmus (upstream) and ductus arteriosus and descending a...

The ductus arteriosus is a specialized blood vessel containing highly differentiated and contractile vascular smooth muscle, derived largely from neural crest cells, that is essential for fetal life but typically closes after birth. Impaired development of the ductus arteriosus or disruption of signaling pathways that initiate postnatal closure can result in persistent patency of the ductus art...