The MRT routing information export format represents an effective way of storing BGP routing information in binary dump files. Although a few tools exist to extract data from MRT dump files, most of them do not allow repacking or creating such MRT files. The MRT dump file manipulation toolkit (MDFMT) allows to repack parts of large MRT dump files containing BGP update messages into smaller ones...

Dynamical modeling is an accurate tool for describing the dynamic regulation of one-carbon metabolism (1CM) with emphasis on the alteration of DNA methylation and/or dUMP methylation into dTMP. Using logic programming we present a comprehensive and adaptative mathematical model to study the impact of folate deficiency, including folate transport and enzymes activities. 5-Methyltetrahydrofolate ...

The MRT routing information export format represents an effective way of storing BGP routing information in binary dump files. Although a few tools exist to extract data from MRT dump files, most of them do not allow repacking or creating such MRT files. The MRT dump file manipulation toolkit (MDFMT) allows to repack parts of large MRT dump files containing BGP update messages into smaller ones...

A high vacuum and temperature compatible viewing dump, made of MACOR, was designed installed in TCV for Vertical ECE experiments the 75–110 GHz frequency range. Measurements dump prior to installation tokamak showed more than 99% absorption incoming radiation. The has remained in-vessel 7 years, protected from direct plasma exposure by carbon tiles. However it still been exposed boron depositio...

background: the municipal solid wastes (msws) are disposed in open dumps, which have no leachate collection and removal system, in the caspian region of iran. leachate readily reaches the nearby water resources such as streams, rivers, lakes, and sea. therefore, understanding the quality and quantity of open dump leachate is vital to the proper treatment of leachate. methods: the leachate sampl...

Techniques have been developed to measure FdUMP, the active metabolite of 5-FUra; thymidylate synthetase (TMP synthase; 5,10-methylenetetrahydrofolate:dUMP C-methyltransferase, EC 2.1.1.45), the target enzyme for this antimetabolite; and dUMP, the substrate that competes with FdUMP for binding to TMP synthetase. As little as 0.02 pmol of FdUMP can be quantitated with a competitive ligand bindin...

The kinetics of the reaction catalyzed by thymidylate synthase from Lactobacillus casei were investigated at pH 6.8 and 30” with the natural isomer of 5,10-methylene5,6,7&tetrahydrofolate ((+)-CH,-H,folate). An apparatus for adding the enzyme to the reaction mixture and rapidly mixing without opening the sample compartment allowed the acquisition of spectrophotometric rate data within a few sec...

Mutant forms of thymidylate synthase (TS) with substitutions at the conserved active site residue, Trp 80, are deficient in the hydride transfer step of the TS reaction. These mutants produce a beta-mercaptoethanol (beta-ME) adduct of the 2'-deoxyuridine-5'-monophosphate (dUMP) exocyclic methylene intermediate. Trp 80 has been proposed to assist hydride transfer by stabilizing a 5,6,7,8-tetrahy...

Knopp et al. @J. Raman Spectrosc. 31, 51 ~2000!# have recently used resonant femtosecond coherent anti-Stokes Raman spectroscopy ~CARS! to prepare and probe highly excited vibrational wave packets on the ground electronic potential surface of molecular iodine. The experiment uses a sequence of three resonant femtosecond pulses with two independently variable time delays. The first two pulses ac...