abstract basement membrane of glomerular mesangium (bmg) is a thin membrane which helps to support the capillary loops in a renal glomerulus and type iv collagen is require for complete bm formation during glomerulogenesis. in this investigation specific antibody of type iv collagen has been used in light microscopy to study development of bmg of the embryonic and postnatal mouse glomerular mes...

A geophysical method of investigation has been deployed in order to give a quick overview the nature and rapidly changing subsurface lithologies that characterized Yikpata, Share, Kwara State, Nigeria. total nine (9) vertical electrical soundings (VES), using Schlumberger Array uniformly divided into three groups: basement, basement/sedimentary boundary sedimentary terrain, horizontal profiling...

The corneas of 12 eye donors with maturity-onset diabetes were obtained, and the corneal epithelial basement membranes were studied by transmission electron microscopy. Similar tissue was obtained from 12 nondiabetic eye donors who were matched for age (within 2 years) and race. The mean thickness of the corneal epithelial basement membrane in nondiabetic patients was 0.33 micrometer (+/- 0.11 ...

We report a case of struma ovarii with hyperthyroidism and elevated serum concentrations of type IV collagen and laminin. Circulating levels of type IV collagen and laminin were measured using specific radioimmunoassays (RIAs) for 7S collagen and the P-1 fragment of laminin, and the basement membrane components in the tumor were investigated by immunohistochemical analysis. Strong immunohistoch...

[1] We use coupled heat and mass transport models to investigate the basement permeability distribution and hydrothermal circulation patterns in an area with large basement relief below flat seafloor on the eastern flank of the Juan de Fuca Ridge. If heat transport around Ocean Drilling Program Sites 1026 and 1027 were purely conductive, the top of basement at Site 1027 (below 600 m of sediment...

Basement membranes are thin, specialized extracellular matrices surrounding most tissues in all metazoans. The compositions and functions of basement membranes have generally been well conserved throughout the subkingdom. Genetic analyses of basement membrane components in C. elegans have provided insights into their assembly and functions during development. Immuno- or GFP-tagged localization ...

Species living under large thermal fluctuations possibly need more flexible physiological capabilities than species living in more stable thermal environments. Deep-soil dwelling species habituate more stable thermal environments than surface dwelling species. We compared the flexibility of lipid composition in response to two acclimation temperatures of soil (4), near surface (2), and surface ...

Hepatocyte growth factor (HGF) is a pulmotrophic factor for the regeneration of injured pulmonary tissue. We investigated the role of HGF in basement membrane formation during wound healing by immortalized alveolar type II epithelial cells that could form a continuous basement membrane when they were cultured on collagen fibrils in the presence of entactin-contaminated laminin-1. Cells cultured...

To metastasize, cancer cells must acquire the ability to breach several basement membrane barriers. Cell invasions through basement membranes also occur during normal development and immune system function, enabling organ formation and cell dispersal. The mechanisms that cells use to cross basement membranes in vivo remain elusive. In cancer and development, these invasions occur in complex and...