Dysgerminoma is an uncommon tumor,accounting for 1-2% of primary ovarian neoplasm and for 35% of ovarian malignancies.Tumor may occur at any age from infancy to old age,but most cases occur in adolescence and early adult life.Dysgerminoma occur not infrequently before puberty but is very rare after menopause.Literature states that about 2% of nonpregnant patient with dysgerminoma present with e...

A case of bilateral gonadoblastoma/dysgerminoma in a 46 XY phenotypical female is presented. Increased circulating beta human chorionic gonadotropin (beta-HCG) and testosterone together with a decreased concentration of follicle stimulating hormone (FSH) reflected the activities of these tumours. The patient is alive and well three years later, after treatment by surgery and cobalt therapy.

BACKGROUND Gonadoblastoma (GB) is regarded as an in situ form of germ cell tumor in dysgenetic gonads, and 30% of patients with GB develop a dysgerminoma/seminoma tumor. OBJECTIVE Determine whether OCT3/4 and β-catenin are expressed in dysgenetic gonads before GB development and whether TSPY participates in the OCT3/4-β-catenin pathways in the malignant invasive behavior. METHODS dysgenetic...

Gonadoblastoma and dysgerminoma developed in a 24-year-old phenotypic female patient with 46,XY pure gonadal dysgenesis. This patient presented with primary amenorrhea. Clinical characteristics showed a typical stigmata of gonadal dysgenesis: primary amenorrhea, sexual infantilism, a small uterus and bilateral streak gonads. A 46,XY karyotype was made by lymphocyte culture. The patient was coun...

Case Report

Here we present the case of a 30-year-old man diagnosed with a dysgerminoma with mediastinal involvement, who developed an isolated chylopericardium during treatment. The purpose of this paper is to review the etiology, diagnosis and new approaches to the treatment of chylopericardium.

A case of comprehensive laparoscopic surgical staging for ovarian dysgerminoma in a 13-year-old girl is described. A 20-cm pelvic mass, rising from right adnexum, was incidentally diagnosed, and the patient underwent laparoscopic right salpingo-oophorectemy. Pathologic findings were consistent with diagnosis of pure dysgerminoma. We then performed laparoscopic staging including peritoneal washi...