OBJECTIVE To study whether there are differences between women and men with regard to the reported level of fatigue, to explore the strength of the relations between fatigue and disease activity, pain, sleep disturbance, mental health, and activity limitation in early rheumatoid arthritis, and to explore the consistency of such findings. DESIGN Analyses and comparisons of cross-sectional data...

In the morning a man walks with his whole body in the evening only with his legs (Emerson). Fatigue is a common symptom. It is responsible for an estimated 10±15 million clinic or office visits annually in the USA. As an isolated symptom, fatigue is seldom a cause for concern. However, fatigue in association with a systemic illness can be ominous. Although interest in understanding the pathogen...

BACKGROUND AND PURPOSE Mechanisms of fatigue reported during radiotherapy are poorly defined but may include inflammatory cytokines and/or sleep disturbances. This prospective, longitudinal, phase II study assessed fatigue, sleep, and serum cytokine levels during radiotherapy for early-stage prostate cancer (PCa). MATERIAL AND METHODS Twenty-eight men undergoing radiotherapy for early-stage P...

Over the past decade, the Texas Department of Transportation (TxDOT) focused research efforts on improving hot mix asphalt concrete (HMAC) mix design to preclude rutting in the early life of pavements. However, these rut-resistant stiff mixtures may be susceptible to long-term fatigue cracking due to oxidative aging. This project completed initial development of an HMAC mixture fatigue design a...

introduction: ifosfamide (ifo) is a potent drug that is used in cancer therapy. the major uses of ifo are: solid tumors especially, osteogenic sarcoma, other soft tissue sarcomas and hematologic malignancy, especially in lymphoma patients. the toxicity of ifo is very encompassing and includes: alopecia, nausea, vomiting, gastrointestinal, renal and neurological problems. neuropsychiatric toxici...

The objective of the current study was twofold: (a) to determine whether subgroups of breast cancer patients could be identified on the basis of their distinct trajectory or pattern of fatigue following treatment for early stage cancer using growth mixture modeling and (b) to examine whether the subgroups could be distinguished on the basis of a cognitive-behavioral model. Growth mixture modeli...

BACKGROUND The postpartum is a time when women commonly report increased fatigue that may contribute to depression. Studies have not examined fatigue alone as a predictor of postpartum depression. OBJECTIVE To examine whether and when fatigue in the early postpartum is predictive of postpartum depression. DESIGN Correlational, longitudinal study. SETTING Two hospitals and participants' ho...

Sitting in our offices early in the morning of September 11, 2001, we, like many across the world, watched with incredulity the twin terrorist strikes on the World Trade Centre. Riveted to the television screen, we witnessed the beginnings of a nightmare whose images will likely remain with us for a long time. September 11, and the events that followed, changed our assumptions of world terroris...

The objective of the study was to evaluate the ability of a nonlinear ultrasound technique, the so-called nonlinear resonant ultrasound spectroscopy (NRUS) technique, for detecting early microdamage accumulation in cortical bone induced by four-point bending fatigue. Small parallelepiped beam-shaped human cortical bone specimens were subjected to cyclic four-point bending fatigue in several ste...