Papillon-Lefèvre syndrome is a rare autosomal recessive genodermatosis characterised by palmoplantar hyperkeratosis and severe early-onset periodontitis. The development of malignant cutaneous neoplasms within the hyperkeratotic lesions of the syndrome is very rare. Here, we report on a 67-year-old German Caucasian male with Papillon-Lefèvre syndrome associated with recurrent squamous cell carc...

The JP2 clone of Actinobacillus actinomycetemcomitans is associated with early-onset periodontitis in certain ethnic populations of African origin. Here, we describe and evaluate a set of primers for PCR to assay for the presence of A. actinomycetemcomitans and to discriminate between JP2-like strains and other genotypes in subgingival plaque samples.

Periodontitis is a multifactorial disease associated with several risk and susceptibility factors (66). Risk factors are part of the causal chain, or expose the host to the causal chain. The presence of a risk factor directly increases the probability of a disease occurring, and the absence of a risk factor reduces this possibility. Risk factors are modifiable. Contrary to modifiable risk facto...

Aggressive periodontitis is a type of periodontitis with early onset and rapid progression and mostly affecting young adults who occupy a large percentage of orthodontic patients. The role of the orthodontist is important in screening the disease, making a provisional diagnosis, and referring it to a periodontist for immediate treatment. The orthodontist should be aware of the disease not only ...

background inflammatory bowel disease (ibd) may begin as early as the first year of life. the objective of the present study was to determine the characteristics and clinical course of children with early-onset ibd. materials and methods the records of patients with ibd admitted to children medical center hospital during 2003-2006 were screened for those with disease onset before the first year...

DEFINITIONS Inflammation: A localized protective response elicited by injury or destruction of tissue, which serves to destroy, dilute, or wall off both the injurious agent and the injured tissue. A cellular and vascular reaction of tissues to injury. Gingivitis: Inflammation of the gingiva. Periodontitis: Inflammation of the supporting tissues of the teeth. Usually a progressively destructive ...

The purpose of this study was to determine whether chronic periodontitis can stand behind the modifications observed in the salivary and blood concentration of some bivalent cations (Calcium, Magnesium, Zinc and Copper). The investigations were performed on an experimental group of 30 patients with clinically-onset chronic periodontitis, and on a control one, including 30 periodontitis-