A 39-year-old non-atopic nurse was referred to our contact allergy unit in November 2012 because of eczematous skin lesions on the arms, neck and trunk of 7-month duration. Initially, the diagnosis of pityriasis rosea of Gibert had been suspected, but a biopsy of a lesion on the trunk had shown a spongiotic dermatitis with eosinophils, compatible with eczema. Application of a cream containing h...

Background: Eczema is one of the most widely spread inflammatory skin disorders contact dermatitis is an eczematous dermatitis that is produced as a result of contact with a substance in the environment. The substance can act as an irritant or allergen. Every country has allergen particular to itself. Objective: Determining the frequency of skin allergens in patients with contact dermatitis in ...

toid, erythematous-vesicular, or urticarial lesions appear on the periphery of and at a distance from the area of the original contact. Histopathology findings are nonspecific. Spongiosis and exocytosis are common findings, although vacuolar degeneration of the basement membrane or epidermal necrolysis is more unusual. Acrylate-induced allergic contact dermatitis usually manifests as eczematous...

Sir, Prurigos are diseases characterized by intensely pruritic papules and nodules caused by a variety of pathomechanisms. Primary lesions are papules, with or without vesicles, or urticarial lesions. Unlike eczematous reactions, the lesions of prurigo rarely become confluent or form lichenified plaque. Prurigo lesions do not show pustule formation or desquamation. However, prurigos can co-exis...

Atopic dermatitis is a multifactorial skin disease. Epidermal barrier dysfunction, bacterial colonisation, psychological stress, but also type I allergens may aggravate this chronic remittent skin disease. Food allergens may play a role as aggravating factors in a subgroup of patients with atopic dermatitis, however the elicitating allergen profile differs between children and adults. In childr...

Allergic contact dermatitis is increasingly being recognized as a disease that affects children in addition to adults. Historically, irritant contact dermatitis such as ‘diaper dermatitis’ was a frequent diagnosis made in children, while allergic contact dermatitis was not considered a significant disease in this age group. Clinicians may have attributed this to children’s lack of exposure to a...

A 5 1/2-year-old girl, with a life-long history of recurrent staphylococcal infections and eczematous dermatitis had a defect in polymorphonuclear leucocyte chemotaxis and phagocytosis in autologous serum, a high serum IgE level, and a disturbed T cell function. Levamisole improved all the immunological abnormalities and there was a dramatic clinical improvement. Discontinuation of therapy with...

Increased dermal mucin is a feature of lupus erythematosus (LE); however, its amount and distribution have not been well characterized. The differentiation of LE from other forms of dermatitis can be challenging when other features of LE are subtle or equivocal. One hundred and thirty-five skin specimens showing LE, graft vs. host disease, erythema multiforme/fixed drug eruption, lichen planus,...

toid, erythematous-vesicular, or urticarial lesions appear on the periphery of and at a distance from the area of the original contact. Histopathology findings are nonspecific. Spongiosis and exocytosis are common findings, although vacuolar degeneration of the basement membrane or epidermal necrolysis is more unusual. Acrylate-induced allergic contact dermatitis usually manifests as eczematous...

toid, erythematous-vesicular, or urticarial lesions appear on the periphery of and at a distance from the area of the original contact. Histopathology findings are nonspecific. Spongiosis and exocytosis are common findings, although vacuolar degeneration of the basement membrane or epidermal necrolysis is more unusual. Acrylate-induced allergic contact dermatitis usually manifests as eczematous...