The dual-tracer method has been used conventionally for assessment of postprandial fluxes, i.e., appearance in plasma of ingested glucose (R(a meal)), endogenous glucose production (EGP), and disposal (R(d)). To quantify the magnitude of errors affecting the calculations and their dependence on model assumptions, this method was assessed and compared with the triple-tracer method, which provide...

We present a synthesis of physical effects influencing the observed lightcurve of an extrasolar giant planet (EGP) transiting its host star. The synthesis includes a treatment of Rayleigh scattering , cloud scattering, refraction, and molecular absorption of starlight in the EGP atmosphere. Of these effects, molecular absorption dominates in determining the transit-derived radius R, for planeta...

We present a synthesis of physical effects influencing the observed lightcurve of an extrasolar giant planet (EGP) transiting its host star. The synthesis includes a treatment of Rayleigh scattering, cloud scattering, refraction, and molecular absorption of starlight in the EGP atmosphere. Of these effects, molecular absorption dominates in determining the transit-derived radius R, for planetar...

Chronic resistive airway loading (CAL) impairs growth in juvenile rats. The effects of CAL on epiphyseal growth plate (EGP) structure and insulin-like growth factor (IGF)-I gene expression have not been explored. Little is known about whether stimulants of endogenous growth hormone (GH) secretion can normalize this growth impairment. This study explored the effect of CAL on circulating and EGP ...

Recently, we proposed a model describing the suppression of endogenous glucose production (EGP) during a meal. It assumes that EGP suppression depends on glucose concentration and its rate of change and on delayed insulin action. Hepatic insulin sensitivity (S(I)(Lmeal)) can be derived from EGP model parameters. This model was shown to adequately describe EGP profiles measured with multiple tra...

The ability to accurately quantify indexes of the individual role of glucose (GE(L)) and insulin (S(I)(L)) in the suppression of endogenous glucose production (EGP) would improve the understanding of liver metabolism. Measuring these indexes during an IVGTT by minimal modeling of tracer labeled and unlabeled glucose data is often unreliable, possibly due to an inadequate description of EGP incl...

OBJECTIVE The hypothalamic neuropeptide orexin influences (feeding) behavior as well as energy metabolism. Administration of exogenous orexin-A into the brain has been shown to increase both food intake and blood glucose levels. In the present study, we investigated the role of endogenous hypothalamic orexin release in glucose homeostasis in rats. RESEARCH DESIGN AND METHODS We investigated t...

Shear zones in the boundary between Eastern Ghats Province (EGP) and cratons of Singhbhum north Bastar west provide an excellent opportunity to study tectonics shear zone development its timing relation evolutionary history granulite suites. Detailed structural, microfabric quartz C-axis patterns revealed a high temperature zone, at western EGP Craton (BC) around Paikmal. Petrological studies t...