this was a prospective cross-sectional study of consecutive transported patients by emergency medical service (ems) to a referral hospital. the goal of this study was the evaluation of emergency medical technician intermediate prediction about their transported patients disposition in emergency department of imam khomeini hospital. 2950 patients were transported to this hospital, questionnaires...

PURPOSE This study aimed to detect cell-surface vimentin (CSV) on the surface of epithelial-mesenchymal transitioned (EMT) circulating tumor cells (CTC) from blood of patients with epithelial cancers. EXPERIMENTAL DESIGN In this study, 101 patients undergoing postsurgery adjuvant chemotherapy for metastatic colon cancer were recruited. EMT CTCs were detected from blood of patients using the 8...

Epithelial-to-mesenchymal transition (EMT) is an important driver of tumor invasion and metastasis, which causes many cancer deaths. Cancer stem cells (CSC) that maintain and initiate tumors have also been implicated in invasion and metastasis, but whether EMT is an important contributor to CSC function is unclear. In this study, we investigated whether a population of CSCs that have undergone ...

Epithelial-mesenchymal transition (EMT) is a complex reversible biological process characterized by the loss of epithelial features and acquisition mesenchymal features. EMT was initially described in developmental processes further associated with pathological conditions including metastatic cascade arising neoplastic progression organ fibrosis. Fibrosis delineated an excessive number myofibro...

Epithelial to mesenchymal transition (EMT) is a process during which cells lose their epithelial characteristics, for instance cell polarity and cell-cell contact, and gain mesenchymal properties, such as increased motility. In colorectal cancer (CRC), EMT is associated with an invasive or metastatic phenotype. In this review, we discuss recent studies exploring novel regulation mechanisms of E...

Epithelial to mesenchymal transition (EMT) is a key trans-differentiation process, which plays a critical role in physiology and pathology. Although gene expression changes in EMT have been scrutinized, study of epigenome is in its infancy. To understand epigenetic changes during TWIST-driven EMT, we used the AcceSssIble assay to study DNA methylation and chromatin accessibility in human mammar...