The application of focused beam reflectance measurement (FBRM) was studied in a larger scale PLGA microparticle preparation process for monitoring changes of the particle size and the particles' surface properties. Further understanding how these parameters determine the chord length distribution (CLD) was gained by means of single object measurements and data of monodisperse microparticles. It...

The aim of this study was to design a simple and reliable method for obtaining the detailed information about the average size, size distribution, and the surface morphology of particles with variation of the sample preparation of a polymer emulsion. In this work, the characteristic features of the particles of rosin size with high viscosity were first described by scanning electron microscopy ...

In this paper we describe a novel method for detecting many DNA fragments through efficient amplification by using an emulsion system based on "on-chip" PCR instead of conventional multiplex polymerase chain reaction (PCR). During the preparation of on-chip PCR, a set of primers were immobilized on a slide and other sets were in an emulsion system. Different emulsion phase primers and other rel...

A numerical investigation of directional binary alloy solidification processes is presented. In particular, a mathematical model is developed to study macrosegregation patterns as a consequence of thermal-solutal convection in the melt and mushy zone. A good understanding of the basic mechanisms of macrosegregation is helpful in designing and controlling solidification processes in order to ach...

Mathematical models and associated numerical techniques have been developed to investigate the complicated transport phenomena in spot hybrid laser-MIG keyhole welding. A continuum formulation is used to handle solid phase, liquid phase, and the mushy zone during the melting and solidification processes. The volume of fluid (VOF) method is employed to handle free surfaces, and the enthalpy meth...

In continuous casting, it is very important to predict and detect the internal cracks of billet in time for ensuring continuous production, improving product quality and reducing production costs. Clustering analysis (CA) method is adopted to do feature extraction and classification for on-site data, by which ladder parameter tables of processing parameters and defect grades of internal cracks ...

The Directional Solidification is a very important technique for growing high quality multi-crystalline silicon at large scale for PV solar cells. The physics governing the growth of multi-crystalline silicon in the Directional Solidification System involves complex non-linear transport phenomena including but not limited to heat transfer, solidification, thermal stress development, and the for...

Background Intravenous drug delivery is an advantageous choice for rapid administration, immediate drug effect, and avoidance of first-pass metabolism in oral drug delivery. In this study, the synthesis, formulation, and characterization of atorvastatin-loaded polyurethane (PU) nanoparticles were investigated for intravenous route of administration. Methods First, PU was synthesized and chara...

All metals and alloys with exception of Bi are shrinking during cooling, mostly during the solidification process. In order to avoid shrinking porosity, casting process, and gating and feeding system must be properly designed. Solidification front must move towards the feeding system where solidification is then completed. No separate liquid pockets where solidification ended without feeding sh...

New processes have been developed in the last years to produce near net shape steel products by continuous casting. This work deals with the analysis of the effects of liquid core reduction during the solidification in the microstructure of thin slabs obtained by continuous cast process. An equipment able to simulate the liquid core reduction during the solidification was projected and construc...