Endometriosis is defined by presence of endometrial glands and stroma outside the uterine cavity and it affects approximately 5%-10% of women of reproductive age. Although endometriosis is usually considered to be due to retrograde menstruation, the true pathogenesis of this disease remains poorly understood. Endometriosis is associated with an inflammatory response and this inflammation leads ...

Despite the publication of numerous studies, including some multicentered randomized controlled trials, there continues to be vigorous debate regarding the optimal management of early stage endometrial cancer, including the extent of surgery and the role of adjuvant chemotherapy and radiation. Resolving these questions has become increasingly important in view of the increase of endometrial can...

endometrial calcification along with ossification is an uncommon clinical entity. most of the cases are asymptomatic or present with secondary infertility. endometrial ossification associated with repeated abortions has been reported very infrequently. here we report a case of endometrial calcification with ossification  due to retained fetal bony tissue in a 38 year old symptomatic female havi...

Background Inherited cancer syndromes associated with acoustic neuroma (i.e. neurofibromatosis 2-NF2), pheochromocytoma (i.e. Von Hippel Lindau, NFl, multiple endocrine neoplasia syndromes, and hereditary paraganglioma syndrome), and colon cancer are well known. Lynch syndrome is the most common hereditary colon cancer syndrome and is caused by DNA mismatch repair dysfunction secondary to inher...

Endometriosis is a common gynecologic condition in which endometrial tissue grows in ectopic locations. It is estimated that 5 million women of reproductive age, or 10 percent of women, in the United States, are affected by this disease.1 Approximately 20 percent of women with chronic pelvic pain and 30–45 percent of women with infertility have endometriosis.2 Endometrial tissue outside the ute...

objective: in order to evaluate the endometrium by ultrasound in patients undergoing controlled ovarian hyperstimulation (coh) with clomiphene citrate (cc) and human menopausal gonadotropin (hmg) with intrauterine insemination (iui) to determine the relationship between endometrial pattern and thickness on pregnancy rate (pr). methods: in this prospective study, 108 infertile couples underwent ...

During the establishment of pregnancy, the ovarian-derived hormones progesterone and oestradiol regulate remodelling of the endometrium to promote an environment that is able to support and maintain a successful pregnancy. Decidualisation is characterised by differentiation of endometrial stromal cells that secrete growth factors and cytokines that regulate vascular remodelling and immune cell ...

objective: the endometrial hyperplasia measured by ultrasound in polycystic ovary syndrome (pcos) women is strongly related to pathologic endometrial thickness, but there is no consensus on the relation between serum luteinizing hormone (lh) and either of these factors: pathologic endometrial hyperplasia and body mass index (bmi). materials and methods: in this observational cross-sectional stu...

background uterine cancer stays the most prevalent gynecologic malignancy in developed countries. providing suitable solutions to treat this disease is required to the early diagnosis of this cancer. objectives the aim of this study was to evaluate the effectiveness of multiple-site lymph node sampling in patients with the endometrioid type of endometrial cancer. patients and methods demographi...