conclusions the lack of difference between adma levels in patients with pa and eh suggests that endothelial dysfunction is more likely related to hypertension per se than to the specific etiology of elevated blood pressure. results patients with pa had significantly higher concentrations of adma than healthy controls (0.488 ± 0.085 vs. 0.433 ± 0.053 μmol/l, p = 0.027). no difference was found i...

introduction: angiogenesis play an important role in many physiological processes (embryonic growth, tissue repair, etc) and also in pathological ones (diabetes, retinopathy, arthritis, tumor growth, etc). evaluation of endothelial cell growth and finally new vessel development in vivo is a complex and often difficult task. materials & methods: to address this issue an in vitro experimental ang...

purpose : to report the long-term outcome of patients with iridocorneal endothelial syndrome (ice) who required surgery for glaucoma. materials & methods : this retrospective, noncomparative case series was conducted on 11 patients with ice who underwent surgery to control their glaucoma between 1992 and 2004 in farabi eye hospital. the first surgery was trabeculectomy with mitomycin c except i...

background: multiple sclerosis (ms) is an autoimmune disease of central nerves system, in which neurological disabilities occur in young adults. despite increasing number of studies on ms, some aspects of this disorder are still unclear. in the previous studies, it has been proven that there is direct relation between ms incidence and vitamin d deficiency. thereby, strong evidence in ms pathoge...

Intravascular papillary endothelial hyperplasia (IPEH) is an uncommon benign vascular disease characterized by endothelial cell proliferation and papillary formation within the lumen of blood vessels arising from an organizing thrombus. The occurrence of this uncommon lesion is about 2% of all vascular tumors. IPEH mostly occurs in the 5th decade of life, and there is no gender or age predilect...

accumulating evidence indicates that aldosterone plays a critical role in the mediation of oxidative stress and vascular damage. nadph oxidase has been recognized as a major source of oxidative stress in vasculature. however, the relation between nadph oxidase in aldosterone-mediated oxidative stress in endothelial cells remains to be ascertained. the present study aimed to investigate the rele...

corneal neovasculariuulon (cnj1 can cause significant visual loss. the kinetics of endothelial cells durin{: microvascular growth were studied usinga model of alkaline cauteriuuion-induced neovascularization ofthe 40 rabbits cornea. changes in dna synthetic activity of endothelial cells during neovasculanuuion were assessed by autoradiographic studyojjjl_tdr incorporation, in vivo and in vitro....

New blood forming vessels are produced by differentiation of mesodermal precursor cells to angioblasts that become endothelial cells (ECs) which in turn give rise to primitive capillary network. Human cord blood (HCB) contains large subsets of mononuclear cells (MNCs) that can be differentiated into endothelial-like cells in vitro. Human mononuclear progenitor cells were purified from fresh umb...